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Case Rep Ophthalmol. 2021 Jan 21;12(1):77-82. doi: 10.1159/000510570. eCollection 2021.

Conjunctival Intraepithelial Neoplasia in a Patient Presenting with Pigmented Conjunctival Lesion.

Case reports in ophthalmology

Winai Chaidaroon, Chutikarn Dejkriengkraikul, Sirawit Isipradit, Nirush Lertprasertsuke

Affiliations

  1. Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  2. Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

PMID: 33613255 PMCID: PMC7879333 DOI: 10.1159/000510570

Abstract

We report a case of conjunctival intraepithelial neoplasia (CIN) in a patient presenting with the pigmented conjunctival lesion. This study involved a 56-year-old woman that presented with right eye irritation for 1 month. She noticed brownish pigmentation arising from her right nasal conjunctiva and growing slowly over time. Biomicroscopic examination showed a gelatinous pigmented conjunctival mass with feeder vessels. Conjunctival impression cytology (CIC) was done and reported as CIN. Treatment was started with 0.02% mitomycin-C eye drops. The conjunctival lesion responded well to medication. This report shows that CIN can manifest as a pigmented tumor, resembling melanoma. CIC plays a role in the diagnosis of this condition. This tumor responded well with 0.02% mitomycin-C eye drops.

Copyright © 2021 by S. Karger AG, Basel.

Keywords: Conjunctival intraepithelial neoplasia; Conjunctival melanoma; Pigmented conjunctival lesion

Conflict of interest statement

There are no conflicts of interest to report for all authors.

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