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Lin SY, Lin SC. SRC promotes lipogenesis: implications for obesity and breast cancer. Mol Cell Oncol. 2021;8(1):1866975doi: 10.1080/23723556.2020.1866975.
Lin, S. Y., & Lin, S. C. (2021). SRC promotes lipogenesis: implications for obesity and breast cancer. Molecular & cellular oncology, 8(1), 1866975. https://doi.org/10.1080/23723556.2020.1866975
Lin, Shu-Yong, and Lin, Sheng-Cai. "SRC promotes lipogenesis: implications for obesity and breast cancer." Molecular & cellular oncology vol. 8,1 (2021): 1866975. doi: https://doi.org/10.1080/23723556.2020.1866975
Lin SY, Lin SC. SRC promotes lipogenesis: implications for obesity and breast cancer. Mol Cell Oncol. 2021 Jan 12;8(1):1866975. doi: 10.1080/23723556.2020.1866975. PMID: 33553613; PMCID: PMC7849727.
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Mol Cell Oncol. 2021 Jan 12;8(1):1866975. doi: 10.1080/23723556.2020.1866975.

SRC promotes lipogenesis: implications for obesity and breast cancer.

Molecular & cellular oncology

Shu-Yong Lin, Sheng-Cai Lin

Affiliations

  1. State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
  2. Department of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, China.

PMID: 33553613 PMCID: PMC7849727 DOI: 10.1080/23723556.2020.1866975

Abstract

Remodeling of lipid metabolism has been implicated in cancers; however, it remains obscure how the lipid metabolic pathways are altered by oncogenic signaling to affect tumor development. We have recently shown that proto-oncogene tyrosine-protein kinase Src interacts with and phosphorylates the lipogenesis enzyme phosphatidate phosphatase LPIN1 to promote breast cancer development.

© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

Keywords: LPIN1; SRC; breast cancer; lipogenesis; phosphatidylethanolamine

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