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Aldrian D, Neu N, Oberhuber G, et al. Pediatric Malignant Peritoneal Mesothelioma With Meningeal Metastasis. J Pediatr Hematol Oncol. 2021;doi: 10.1097/MPH.0000000000002118.
Aldrian, D., Neu, N., Oberhuber, G., Kropshofer, G., Müller, T., & Vogel, G. F. (2021). Pediatric Malignant Peritoneal Mesothelioma With Meningeal Metastasis. Journal of pediatric hematology/oncology, . https://doi.org/10.1097/MPH.0000000000002118
Aldrian, Denise, et al. "Pediatric Malignant Peritoneal Mesothelioma With Meningeal Metastasis." Journal of pediatric hematology/oncology vol. (2021). doi: https://doi.org/10.1097/MPH.0000000000002118
Aldrian D, Neu N, Oberhuber G, Kropshofer G, Müller T, Vogel GF. Pediatric Malignant Peritoneal Mesothelioma With Meningeal Metastasis. J Pediatr Hematol Oncol. 2021 Feb 25; doi: 10.1097/MPH.0000000000002118. Epub 2021 Feb 25. PMID: 33633025.
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J Pediatr Hematol Oncol. 2021 Feb 25; doi: 10.1097/MPH.0000000000002118. Epub 2021 Feb 25.

Pediatric Malignant Peritoneal Mesothelioma With Meningeal Metastasis.

Journal of pediatric hematology/oncology

Denise Aldrian, Nikolaus Neu, Georg Oberhuber, Gabriele Kropshofer, Thomas Müller, Georg-Friedrich Vogel

Affiliations

  1. Department of Paediatrics I Institute of Cell Biology, Medical University of Innsbruck INNPATH, Tirol-Kliniken University Hospital Innsbruck, Innsbruck, Austria.

PMID: 33633025 DOI: 10.1097/MPH.0000000000002118

Abstract

Malignant peritoneal mesothelioma (MPM) is an extremely rare entity with a poor prognosis. We report on a 16-year-old boy with ascites and abdominal distension. A computed tomography scan showed peritoneal thickening and a mass adjacent to the transverse colon. Neither repeated cytologic testing of ascitic fluid, nor peritoneal tissue biopsy detected malignant cells. After the patient became progressively comatose, a magnetic resonance imaging scan of the brain showed leptomeningeal enhancement. An autopsy showed MPM infiltrating the pleura and the meninges. This is the first report on meningeal metastasis of MPM in a pediatric patient illustrating the enigmatic behavior of the tumor and highlighting the diagnostic pitfalls.

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Conflict of interest statement

The authors declare no conflict of interest.

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