World J Pediatr. 2021 Feb;17(1):85-91. doi: 10.1007/s12519-020-00406-9. Epub 2021 Feb 09.
ECIEN-2020 study: the effect of COVID-19 on admissions for non-COVID-19 diseases.
World journal of pediatrics : WJP
Beatriz Ramos-Lacuey, Mercedes Herranz Aguirre, Clara Calderón Gallego, Andrea Ilundain López de Munain, Eva Gembero Esarte, Laura Moreno-Galarraga
Affiliations
Affiliations
- Department of Pediatrics, CHN, Complejo Hospitalario de Navarra, Servicio Navarro de Salud, C/Irunlarrea 3, 31080, Pamplona, Spain.
- Pediatric Infectious Diseases Department, CHN, Complejo Hospitalario de Navarra, Servicio Navarro de Salud, Pamplona, Spain.
- Pediatric Hospitalization, Department of Pediatrics, CHN, Complejo Hospitalario de Navarra, Servicio Navarro de Salud, Pamplona, Spain.
- IdiSNA, Navarra Institute for Health Research, Pamplona, Spain.
- Department of Pediatrics, CHN, Complejo Hospitalario de Navarra, Servicio Navarro de Salud, C/Irunlarrea 3, 31080, Pamplona, Spain. [email protected].
- IdiSNA, Navarra Institute for Health Research, Pamplona, Spain. [email protected].
- Department of Preventive Medicine and Public Health, School of Medicine, University of Navarra, Pamplona, Spain. [email protected].
- Pediatric Pulmonology, Department of Pediatrics, CHN, Complejo Hospitalario de Navarra, Servicio Navarro de Salud, Pamplona, Spain. [email protected].
PMID: 33559813
PMCID: PMC7871166 DOI: 10.1007/s12519-020-00406-9
Abstract
BACKGROUND: The pandemic caused by severe acute respiratory coronavirus 2 (SARS-CoV-2) has had great effects on health systems worldwide, not only in relation to coronavirus disease 2019 (COVID-19) cases but also affecting patients with other pathologies.
METHODS: ECIEN-2020 is an observational study conducted in a tertiary referral hospital in Navarra, Spain. It describes the effects of COVID-19 pandemic and the preventive measures adopted, in pediatric admissions for non-COVID-19 diseases. Admissions during March-June 2020 (first wave of the COVID-19 pandemic in Spain) are described and compared with the same quarter in 2019. A sub-analysis was performed delving into epidemiology. Patient characteristics (age, sex, past medical history), disease characteristics (symptoms, duration of symptoms, previous consultation in Primary Care Health Center), and admission characteristics (place and average stay) were analyzed.
RESULTS: A 33% reduction in the number of pediatric hospital admissions was observed, decreasing from 529 hospitalizations in 2019 to 353 in 2020 (P < 0.001). This highlights a 48% reduction in patients admitted for pulmonary diseases. There were no significant changes in average hospital-stay, percentage of intensive care unit admissions, or in admissions for other reasons. Percentage of patients admitted among those seen in the emergency department rose from 5.1% in 2019 to 10.9% in 2020, whereas the total number of consultations in the emergency department decreased by 68%.
CONCLUSION: The pandemic and the measures adopted due to SARS-CoV-2 have significantly decreased pediatric admissions for non-COVID-19 diseases, especially due to a reduction in the hospitalization for respiratory diseases.
Keywords: Admission; COVID-19; Hospitalization; SARS-CoV-2
References
- World Health Organization. Statement on the second meeting of the International Health Regulations. Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). 2005. https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-nCov) . Accessed 24 Jul 2020. - PubMed
- Blumenthal D, Fowler EJ, Abrams M, Collins SR. COVID-19-implications for the health care system. N Engl J Med. 2020;383:1483–8. - PubMed
- Khullar D, Bond AM, Schpero WL. COVID-19 and the financial health of US hospitals. JAMA. 2020;323:2127–8. - PubMed
- Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579:270–3. - PubMed
- Ministry of the Presidency. Royal Decree 463/2020. Volume 67, Official State Bulletin. 2020. https://www.boe.es/buscar/pdf/2020/BOE-A-2020-3692-consolidado.pdf . Accessed 24 Jul 2020 (in Spanish). - PubMed
- Sánchez-Villena AR, de La Fuente-Figuerola V. COVID-19: quarantine, isolation, social distancing and lockdown: are they the same? An Pediatr (Barc). 2020;93:73–4. - PubMed
- Roberts MG. The pluses and minuses of R - PubMed
- Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33. - PubMed
- Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395:470–3. - PubMed
- Scaramuzza A, Tagliaferri F, Bonetti L, Soliani M, Morotti F, Bellone S, et al. Changing admission patterns in paediatric emergency departments during the COVID-19 pandemic. Arch Dis Child. 2020;105:704–6. - PubMed
- Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145:e20200702. - PubMed
- Cai J, Xu J, Lin D, Yang Z, Xu L, Qu Z, et al. A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020;71:1547–51. - PubMed
- Liu W, Zhang Q, Chen J, Xiang R, Song H, Shu S, et al. Detection of Covid-19 in children in early January 2020 in Wuhan, China. N Engl J Med. 2020;382:1370–1. - PubMed
- Calvo C, García LHM, de Carlos VJC, Vázquez MJL, Spanish Paediatric Association Working Group on COVID-19 in Collaboration with the Health Ministry. Recommendations on the clinical management of the COVID-19 infection by the «new coronavirus» SARS-CoV2. Spanish Paediatric Association working group. An Pediatr (Engl Ed). 2020;92:241.e1–11 (in English, Spanish). - PubMed
- Tagarro A, Epalza C, Santos M, Sanz-Santaeufemia FJ, Otheo E, Moraleda C, et al. Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain. JAMA Pediatr. 2020. https://doi.org/10.1001/jamapediatrics.2020.1346 . - PubMed
- Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang ZJ. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. 2020;323:1313–4. - PubMed
- Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663–5. - PubMed
- Chen ZM, Fu JF, Shu Q, Chen YH, Hua CZ, Li FB, et al. Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus. World J Pediatr. 2020;16:240–6. - PubMed
- Moreno-Galarraga L, Urretavizcaya-Martínez M, Echauri JA, Howard MG, García ER, Aguilera-Albesa S, et al. SARS-CoV-2 infection in children requiring hospitalization: the experience of Navarra, Spain. World J Pediatr. 2020;16:614–22. - PubMed
- García-howard M, Herranz-aguirre M, Moreno-Galarraga L, Urretavizcaya-Martínez M, Alegría-Echauri J, Gorría-Redondo N, et al. Case report: benign infantile seizures temporally associated with COVID-19. Front Pediatr. 2020;8:507. - PubMed
- Gutierrez-Jimeno M, Sada AI, Gavira JJ, Cebrian-Nebot C, de Aguilar VA. Severe cardiac and abdominal manifestations without lung involvement in a child with COVID-19. Intern J Clin Pediatr. 2020;9:92–7. - PubMed
- Moreno-Galarraga L, Taveras EM. COVID-19 disease in children: not as mild as we have been led to believe. World J Pediatr. 2020;16:426–7. - PubMed
- Isba R, Edge R, Jenner R, Broughton E, Francis N, Butler J. Where have all the children gone? Decreases in paediatric emergency department attendances at the start of the COVID-19 pandemic of 2020. Arch Dis Child. 2020;105:704. - PubMed
- Luna Tomás MA, Margelí Vila M, Ríos GC. Influence of the 2019-novel coronavirus pandemic on the management of breast cancer. Clin Invest Ginecol Obstet. 2020;47:89–90. - PubMed
- Velayos M, Muñoz-Serrano AJ, Estefanía-Fernández K, Sarmiento-Caldas MC, Moratilla-Lapeña L, López-Santamaría M, et al. Influence of the coronavirus 2 (SARS-CoV-2) pandemic on acute appendicitis. An Pediatr (Engl Ed). 2020;93:118–22. - PubMed
- Navarre Institute of Statistics. Autonomous Community of Navarre. Provisional data January. 2020. https://www.navarra.es/home_es/Gobierno+de+Navarra/Organigrama/Los+departamentos/Economia+y+Hacienda/Organigrama/Estructura+Organica/Instituto+Estadistica/ . Accessed 24 Jul 2020 (in Spanish). - PubMed
- Government of Navarre. Impact and situation-coronavirus. Navarre’s Open Government. 2020. https://gobiernoabierto.navarra.es/es/coronavirus/impacto-situacion . Accessed 24 Jul 2020 (in Spanish). - PubMed
- Institute of Public Health and Labor of Navarra. Progress report COVID-19-20200412. 2020;2:1–2028. http://www.navarra.es/home_es/Gobierno+de+Navarra/Epidemiologia/InformesVigilanciaEpidemiologia2020.htm . Acceseed 1 Sep 2020 (in Spanish). - PubMed
- Willmott M, Nicholson A, Busse H, Macarthur GJ, Brookes S, Campbell R. Effectiveness of hand hygiene interventions in reducing illness absence among children in educational settings: a systematic review and meta-analysis. Arch Dis Child. 2016;101:42–50. - PubMed
- Pollán M, Pérez-Gómez B, Pastor-Barriuso R, Oteo J, Hernán MA, Pérez-Olmeda M, et al. Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study. Lancet. 2020;396:535–44. - PubMed
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