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Koeppen M, Rosenberger P, Magunia H. COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis. Clin Med Insights Circ Respir Pulm Med. 2021;15:1179548421992327doi: 10.1177/1179548421992327.
Koeppen, M., Rosenberger, P., & Magunia, H. (2021). COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis. Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 151179548421992327. https://doi.org/10.1177/1179548421992327
Koeppen, Michael, et al. "COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis." Clinical medicine insights. Circulatory, respiratory and pulmonary medicine vol. 15 (2021): 1179548421992327. doi: https://doi.org/10.1177/1179548421992327
Koeppen M, Rosenberger P, Magunia H. COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis. Clin Med Insights Circ Respir Pulm Med. 2021 Feb 01;15:1179548421992327. doi: 10.1177/1179548421992327. eCollection 2021. PMID: 33597813; PMCID: PMC7863147.
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Clin Med Insights Circ Respir Pulm Med. 2021 Feb 01;15:1179548421992327. doi: 10.1177/1179548421992327. eCollection 2021.

COVID-19 Related Cardiovascular Comorbidities and Complications in Critically Ill Patients: A Systematic Review and Meta-analysis.

Clinical medicine insights. Circulatory, respiratory and pulmonary medicine

Michael Koeppen, Peter Rosenberger, Harry Magunia

Affiliations

  1. Department of Anaesthesiology and Intensive Care Medicine, University Hospital Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany.

PMID: 33597813 PMCID: PMC7863147 DOI: 10.1177/1179548421992327

Abstract

OBJECTIVE: This systematic-review and meta-analysis aimed to assess the prevalence of cardiovascular comorbidities and complications in ICU-admitted coronavirus disease 2019 (COVID-19) patients.

DATA SOURCES: PubMed and Web of Science databases were referenced until November 25, 2020.

DATA EXTRACTION: We extracted retrospective and prospective observational studies on critically ill COVID-19 patients admitted to an intensive care unit. Only studies reporting on cardiovascular comorbidities and complications during ICU therapy were included.

DATA SYNTHESIS: We calculated the pooled prevalence by a random-effects model and determined heterogeneity by Higgins'

RESULTS: Of the 6346 studies retrieved, 29 were included in this review. The most common cardiovascular comorbidity was arterial hypertension (50%; 95% confidence interval [CI], 0.42-058;

CONCLUSIONS: Cardiovascular complications are common in patients admitted to the intensive care unit for COVID-19. However, the existing evidence is highly heterogeneous in terms of study design and outcome measurements. Thus, prospective, observational studies are needed to determine the impact of cardiovascular complications on patient outcome in critically ill COVID-19 patients.

© The Author(s) 2021.

Keywords: COVID-19; cardiovascular system; critical care; heart; hemodynamic

Conflict of interest statement

Declaration of conflicting interests:The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: MK and PR have n

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