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Ha MS, Yook JS, Lee M, et al. Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome. Sci Rep. 2021;11(1):5175doi: 10.1038/s41598-021-84301-x.
Ha, M. S., Yook, J. S., Lee, M., Suwabe, K., Jeong, W. M., Kwak, J. J., & Soya, H. (2021). Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome. Scientific reports, 11(1), 5175. https://doi.org/10.1038/s41598-021-84301-x
Ha, Min-Seong, et al. "Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome." Scientific reports vol. 11,1 (2021): 5175. doi: https://doi.org/10.1038/s41598-021-84301-x
Ha MS, Yook JS, Lee M, Suwabe K, Jeong WM, Kwak JJ, Soya H. Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome. Sci Rep. 2021 Mar 04;11(1):5175. doi: 10.1038/s41598-021-84301-x. PMID: 33664334; PMCID: PMC7933410.
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Sci Rep. 2021 Mar 04;11(1):5175. doi: 10.1038/s41598-021-84301-x.

Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome.

Scientific reports

Min-Seong Ha, Jang Soo Yook, Minchul Lee, Kazuya Suwabe, Woo-Min Jeong, Jae-Jun Kwak, Hideaki Soya

Affiliations

  1. Department of Sports Culture, College of the Arts, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Jung-gu, Seoul, 04620, Republic of Korea. [email protected].
  2. Division of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan. [email protected].
  3. Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sports Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan. [email protected].
  4. Center for Functional Connectomics, Brain Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  5. Department of Sports Medicine, College of Health Science, CHA University, 120 Haeryong-ro, Pocheon-si, Gyeonggi-do, 11160, Republic of Korea.
  6. Division of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan.
  7. Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sports Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan.
  8. Faculty of Health and Sport Sciences, Ryutsu Keizai University, Ibaraki, 301-8555, Japan.
  9. WellCare Korea Co. Ltd., 26 Wadong-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15265, Republic of Korea.
  10. Department of National Defense Technology, Woosuk University, Daehak-ro 66, Jincheon-eup, Jincheon-gun, Chungcheongbuk-do, 27841, Republic of Korea.
  11. Division of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan. [email protected].
  12. Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sports Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan. [email protected].

PMID: 33664334 PMCID: PMC7933410 DOI: 10.1038/s41598-021-84301-x

Abstract

The prevalence of metabolic syndrome (MS) is increasing among the elderly, and new lifestyle-based treatment strategies are warranted. We conducted a randomized, double-blind controlled trial of the effects of aquatic exercise (AE) and/or consumption of burdock root extract (BE) on body composition and serum sex hormones, i.e., testosterone, estradiol, sex hormone-binding globulin (SHBG), and dehydroepiandrosterone-sulfate (DHEA-S) in elderly women with MS. The percentage of abdominal fat was decreased in the AE group. Waist circumference was increased in the control (CON) group, but not in the other groups. SHBG and estradiol levels were enhanced by both AE and BE and correlated with changes in fat-related body composition. DHEA-S levels only increased in the BE group, which was consistent with changes in lean body mass. Testosterone levels decreased in the CON group, which correlated with changes in lean body mass, skeletal muscle mass, body fat, and waist circumference. Our findings suggested that the combined AE/BE intervention exerted no synergistic and/or additive effects on any sex-related outcome measures in elderly women with MS.

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