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Balash Y, Korczyn AD, Khmelev N, et al. Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships. Front Neurol. 2021;12:613991doi: 10.3389/fneur.2021.613991.
Balash, Y., Korczyn, A. D., Khmelev, N., Eilam, A., Adi, M., & Gilad, R. (2021). Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships. Frontiers in neurology, 12613991. https://doi.org/10.3389/fneur.2021.613991
Balash, Yacov, et al. "Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships." Frontiers in neurology vol. 12 (2021): 613991. doi: https://doi.org/10.3389/fneur.2021.613991
Balash Y, Korczyn AD, Khmelev N, Eilam A, Adi M, Gilad R. Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships. Front Neurol. 2021 Feb 25;12:613991. doi: 10.3389/fneur.2021.613991. eCollection 2021. PMID: 33732205; PMCID: PMC7959761.
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Front Neurol. 2021 Feb 25;12:613991. doi: 10.3389/fneur.2021.613991. eCollection 2021.

Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships.

Frontiers in neurology

Yacov Balash, Amos D Korczyn, Nadejda Khmelev, Anda Eilam, Meital Adi, Ronit Gilad

Affiliations

  1. Department of Neurology, Kaplan Medical Center, Rehovot, Israel.
  2. Department of Neurology, Tel-Aviv University, Tel Aviv, Israel.

PMID: 33732205 PMCID: PMC7959761 DOI: 10.3389/fneur.2021.613991

Abstract

Only a few case reports of stroke-like onset of Creutzfeldt-Jakob disease (CJD) have previously been published. We aimed to analyze the neurological, imaging, electroencephalographic (EEG), and laboratory features of patients with this very rare phenomenon. Here, we review the clinical characteristics, onset features, and clinical course variants of stroke-like CJD in 23 such patients. The median age of the patients was 71 years (range: 56-84 years); 12 were women. In 20 patients, CJD was sporadic. Thirteen patients developed apoplexy-like onset of symptoms, whereas the others had prodromal non-specific complaints. Most often the patients manifested with pyramidal signs (

Copyright © 2021 Balash, Korczyn, Khmelev, Eilam, Adi and Gilad.

Keywords: Creutzfeldt-Jakob disease; cerebro-vascular accident; diagnosis; differential diagnosis; stroke

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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