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Riecke K, Müller V, Weide R, et al. Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores. Cancers (Basel). 2021;13(4)doi: 10.3390/cancers13040844.
Riecke, K., Müller, V., Weide, R., Schmidt, M., Park-Simon, T. W., Möbus, V., Mundhenke, C., Polasik, A., Lübbe, K., Hesse, T., Laakmann, E., Thill, M., A Fasching, P., Denkert, C., Fehm, T., Nekljudova, V., Rey, J., Loibl, S., & Witzel, I. (2021). Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores. Cancers, 13(4), . https://doi.org/10.3390/cancers13040844
Riecke, Kerstin, et al. "Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores." Cancers vol. 13,4 (2021). doi: https://doi.org/10.3390/cancers13040844
Riecke K, Müller V, Weide R, Schmidt M, Park-Simon TW, Möbus V, Mundhenke C, Polasik A, Lübbe K, Hesse T, Laakmann E, Thill M, A Fasching P, Denkert C, Fehm T, Nekljudova V, Rey J, Loibl S, Witzel I. Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores. Cancers (Basel). 2021 Feb 17;13(4). doi: 10.3390/cancers13040844. PMID: 33671376; PMCID: PMC7922206.
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Cancers (Basel). 2021 Feb 17;13(4). doi: 10.3390/cancers13040844.

Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores.

Cancers

Kerstin Riecke, Volkmar Müller, Rudolf Weide, Marcus Schmidt, Tjoung-Won Park-Simon, Volker Möbus, Christoph Mundhenke, Arkadius Polasik, Kristina Lübbe, Tobias Hesse, Elena Laakmann, Marc Thill, Peter A Fasching, Carsten Denkert, Tanja Fehm, Valentina Nekljudova, Julia Rey, Sibylle Loibl, Isabell Witzel

Affiliations

  1. Department of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.
  2. Oncological Outpatient Department, Neversstraße 5, 56068 Koblenz, Germany.
  3. Department of Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131 Mainz, Germany.
  4. Department of Gynecology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
  5. Department of Hematology and Oncology, University Hospital Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
  6. Clinic Bayreuth, Preuschwitzer Str. 101, 95445 Bayreuth, Germany.
  7. Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
  8. Department of Gynecology and Obstetrics, University Medical Center Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.
  9. Breast Center, Diakovere Henriettenstift, Schwemannstraße 17, 30559 Hannover, Germany.
  10. Department of Gynecology, Agaplesion Diakonie Clinic Rotenburg, Elise-Averdieck-Straße 17, 27356 Rotenburg, Germany.
  11. Department of Gynecology and gynecologic Oncology ,Agaplesion Markus Hospital, Wilhelm-Epstein-Str. 4, 60341 Frankfurt am Main Frankfurt, Germany.
  12. Department of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Universitätsstraße 21-23, 91054 Erlangen, Germany.
  13. Institute of Pathology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.
  14. Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
  15. German Breast Group, Martin-Behaim-Straße 12, 63263 Neu-Isenburg, Germany.

PMID: 33671376 PMCID: PMC7922206 DOI: 10.3390/cancers13040844

Abstract

Several scores have been developed in order to estimate the prognosis of patients with brain metastases (BM) by objective criteria. The aim of this analysis was to validate all three published graded-prognostic-assessment (GPA)-scores in a subcohort of 882 breast cancer (BC) patients with BM in the Brain Metastases in the German Breast Cancer (BMBC) registry. The median age at diagnosis of BM was 57 years. All in all, 22.3% of patients (

Keywords: brain metastases; breast cancer; prognostic scores

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