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Rheumatology (Oxford). 2021 Mar 17; doi: 10.1093/rheumatology/keab272. Epub 2021 Mar 17.

Ultrasound, magnetic resonance imaging and radiography of the finger joints in psoriatic arthritis patients.

Rheumatology (Oxford, England)

Ari Polachek, Victoria Furer, Mirna Zureik, Sharon Nevo, Liran Mendel, David Levartovsky, Jonathan Wollman, Valerie Aloush, Reut Tzemah, Ofir Elalouf, Marina Anouk, Mark Berman, Ilana Kaufman, Yael Lahat, Hagit Sarbagil-Maman, Sara Borok, Adi Broyde, Lihi Eder, Daphna Paran, Moshe Iluz, Iris Eshed, Ori Elkayam

Affiliations

  1. Department of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
  2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  3. Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Canada.
  4. Radiology Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
  5. Radiology Department, Sheba Medical Center, Tel Hashomer, Israel.

PMID: 33734348 DOI: 10.1093/rheumatology/keab272

Abstract

OBJECTIVE: To report the discrepancies and agreements between ultrasound (US), magnetic resonance imaging (MRI) and radiography of the hand in psoriatic arthritis (PsA), and to compare the sensitivity and specificity of US and radiography to MRI as the gold standard imaging study in PsA.

METHODS: All of the 100 prospectively recruited consecutive PsA patients underwent clinical assessment and concomitant radiographic, US and MRI studies of the metacarpophalangeal, proximal interphalangeal and distal interphalangeal joints of one hand. Synovitis, flexor tenosynovitis, extensor paratenonitis, erosions and bone proliferations were identified and scored. All readers were blinded to clinical data, and agreement was calculated based on prevalence-adjusted bias-adjusted kappa (PABAK).

RESULTS: The prevalence of synovitis, flexor tenosynovitis, extensor paratenonitis and erosions was similar for US and MRI, while that of bone proliferation was significantly increased in US and radiography compared to MRI (P < 0.001). The absolute agreement between US and MRI was good-to-very good for synovitis (85%-96%, PABAK=0.70-0.92), flexor tenosynovitis (93%-98%, PABAK=0.87-0.96), and extensor paratenonitis (95%-98%, PABAK=0.90-0.97). Agreement between US, MRI and radiography was 96%-98% (PABAK=0.92-0.97) for erosions and 71%-93% (PABAK=0.47-0.87) for bone proliferations. Sensitivity of US with MRI as gold standard was higher for synovitis (0.5-0.86) and extensor paratenonitis (0.63-0.85) than for flexor tenosynovitis (0.1-0.75), while the specificity was high for each pathology (0.89-0.98).

CONCLUSION: There is very good agreement between US and MRI for the detection of inflammatory changes in finger joints in PsA. US, radiography and MRI have a good-to-very good agreement for destructive changes.

© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: [email protected].

Keywords: destructive change; finger joints; hand; magnetic resonance imaging; psoriatic arthritis; radiography; ultrasound

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