Display options
Cite
Yoon YH, Park GM, Lee JY, et al. Association of Stage 1 Hypertension Defined by the ACC/AHA 2017 Guideline With Asymptomatic Coronary Atherosclerosis. Am J Hypertens. 2021;34(8):858-866doi: 10.1093/ajh/hpab051.
Yoon, Y. H., Park, G. M., Lee, J. Y., Lee, J. H., Lee, H., Roh, J. H., Kim, J. H., Lee, P. H., Choe, J., Kim, Y. H., & Lee, S. W. (2021). Association of Stage 1 Hypertension Defined by the ACC/AHA 2017 Guideline With Asymptomatic Coronary Atherosclerosis. American journal of hypertension, 34(8), 858-866. https://doi.org/10.1093/ajh/hpab051
Yoon, Yong-Hoon, et al. "Association of Stage 1 Hypertension Defined by the ACC/AHA 2017 Guideline With Asymptomatic Coronary Atherosclerosis." American journal of hypertension vol. 34,8 (2021): 858-866. doi: https://doi.org/10.1093/ajh/hpab051
Yoon YH, Park GM, Lee JY, Lee JH, Lee H, Roh JH, Kim JH, Lee PH, Choe J, Kim YH, Lee SW. Association of Stage 1 Hypertension Defined by the ACC/AHA 2017 Guideline With Asymptomatic Coronary Atherosclerosis. Am J Hypertens. 2021 Aug 09;34(8):858-866. doi: 10.1093/ajh/hpab051. PMID: 33735371.
Copy Download .nbib Format: NLM
Share it on

Am J Hypertens. 2021 Aug 09;34(8):858-866. doi: 10.1093/ajh/hpab051.

Association of Stage 1 Hypertension Defined by the ACC/AHA 2017 Guideline With Asymptomatic Coronary Atherosclerosis.

American journal of hypertension

Yong-Hoon Yoon, Gyung-Min Park, Jong-Young Lee, Jae-Hwan Lee, Hanbyul Lee, Jae-Hyung Roh, Ju Hyeon Kim, Pil Hyung Lee, Jaewon Choe, Young-Hak Kim, Seung-Whan Lee

Affiliations

  1. Department of Cardiology, Chungnam National University Sejong Hospital, Chungnam National University School of Medicine, Sejong, Korea.
  2. Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
  3. Division of Cardiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
  4. Department of Statistics, Kyungpook National University, Daegu, Korea.
  5. Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  6. Department of Health Medicine, Health Screening & Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

PMID: 33735371 DOI: 10.1093/ajh/hpab051

Abstract

BACKGROUND: This study sought to assess the relationship between stage 1 hypertension and subclinical coronary atherosclerosis.

METHODS: A total of 4,666 individuals with available coronary computed tomography angiography (CCTA) results from a health checkup were enrolled. The classification of hypertension was adapted from the American College of Cardiology/American Heart Association (ACC/AHA) 2017 guideline. The presence of coronary plaques and its characteristics, and other CCTA findings were assessed.

RESULTS: There was a linear relationship between blood pressure (BP), both systolic BP (SBP) and diastolic BP (DBP), and the presence of coronary plaque. Patients were classified into 4 groups according to the BP category: normal BP (SBP <120 mm Hg and DBP <80 mm Hg; n = 2,395; 51.3%), elevated BP (SBP 120-129 mm Hg and DBP <80 mm Hg; n = 467; 10.0%), stage 1 hypertension (SBP 130-139 mm Hg or DBP 80-89 mm Hg; n = 1,139; 24.4%), and stage 2 hypertension (SBP ≥140 mm Hg or DBP ≥90 mm Hg; n = 665; 14.2%). Compared with the normal BP group after multivariate adjustment, the stage 1 hypertension group was significantly associated with the presence of atherosclerotic plaque (adjusted odds ratio [95% confidential interval], 1.37 [1.17-1.62]; P < 0.001), especially in noncalcified and mixed plaques. The relationship between stage 1 hypertension and stenosis >50% was not statistically significant. Isolated diastolic and isolated systolic stage 1 hypertensions were significantly related to the presence of coronary plaque. The elevated BP group was not associated with any positive CCTA findings.

CONCLUSIONS: Stage 1 hypertension was independently associated with subclinical coronary atherosclerosis.

© American Journal of Hypertension, Ltd 2021. All rights reserved. For Permissions, please email: [email protected].

Keywords: blood pressure; coronary atherosclerosis; coronary computed tomography angiography; hypertension

Publication Types