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Alcazar JL, Carazo P, Pegenaute L, et al. Präoperative Bewertung der Zervixbeteiligung bei Endometriumkarzinom mittels transvaginalen Ultraschalls und Magnetresonanztomografie: Ein systematischer Review und Metaanalyse. Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis. Ultraschall Med. 2021;doi: 10.1055/a-1408-2292.
Alcazar, J. L., Carazo, P., Pegenaute, L., Gurrea, E., Campos, I., Neri, M., Pascual, M. A., & Guerriero, S. (2021). Präoperative Bewertung der Zervixbeteiligung bei Endometriumkarzinom mittels transvaginalen Ultraschalls und Magnetresonanztomografie: Ein systematischer Review und Metaanalyse. Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis. Ultraschall in der Medizin (Stuttgart, Germany : 1980), . https://doi.org/10.1055/a-1408-2292
Alcazar, Juan Luis, et al. "Präoperative Bewertung der Zervixbeteiligung bei Endometriumkarzinom mittels transvaginalen Ultraschalls und Magnetresonanztomografie: Ein systematischer Review und Metaanalyse." Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis. Ultraschall in der Medizin (Stuttgart, Germany : 1980) vol. (2021). doi: https://doi.org/10.1055/a-1408-2292
Alcazar JL, Carazo P, Pegenaute L, Gurrea E, Campos I, Neri M, Pascual MA, Guerriero S. Präoperative Bewertung der Zervixbeteiligung bei Endometriumkarzinom mittels transvaginalen Ultraschalls und Magnetresonanztomografie: Ein systematischer Review und Metaanalyse. Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis. Ultraschall Med. 2021 Mar 23; doi: 10.1055/a-1408-2292. Epub 2021 Mar 23. PMID: 33757136.
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Ultraschall Med. 2021 Mar 23; doi: 10.1055/a-1408-2292. Epub 2021 Mar 23.

Preoperative Assessment of Cervical Involvement in Endometrial Cancer by Transvaginal Ultrasound and Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)

Juan Luis Alcazar, Patricia Carazo, Leyre Pegenaute, Elena Gurrea, Irene Campos, Manuela Neri, Maria Angela Pascual, Stefano Guerriero

Affiliations

  1. Obstetrics and Gynecology, University of Navarra Clinic, Pamplona, Spain.
  2. Obstetrics and Gynecology, University Hospital Complex Badajoz, Spain.
  3. Obstetrics and Gynecology, Araba University Hospital Txagorritxu Campus, Vitoria-Gasteiz, Spain.
  4. Obstetrics and Gynecology, Virgen de la Arrixaca University Hospital, El Palmar, Spain.
  5. Obstetrics and Gynecology, Università degli Studi di Cagliari, Italy.
  6. Obstetrics and Gynecology, Institut Universitari Dexeus, Barcelona, Spain.

PMID: 33757136 DOI: 10.1055/a-1408-2292

Abstract

OBJECTIVE:  To compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting cervical infiltration by endometrial carcinoma using meta-analysis assessment.

METHODS:  An extensive search of papers comparing TVS and MRI for assessing cervical infiltration in endometrial cancer in the same set of patients was performed in Medline (Pubmed), Web of Science, and the Cochrane Database. Quality was assessed using QUADAS-2 tool (Quality Assessment of Diagnostic Accuracy Studies-2). Quantitative meta-analysis was performed.

RESULTS:  Our extended search identified 12 articles that used both techniques in the same set of patients and were included in the meta-analysis. The risk of bias for most studies was high for patient selection and index tests in QUADAS-2. Overall, the pooled estimated sensitivity and specificity for diagnosing cervical infiltration in women with endometrial cancer were identical for both techniques [69 % (95 % CI, 51 %-82 %) and 93 % (95 % CI, 90 %-95 %) for TVS, and 69 % (95 % CI, 57 %-79 %) and 91 % (95 % CI, 90 %-95 %) for MRI, respectively]. No statistical differences were found when comparing both methods. Heterogeneity was high for sensitivity and moderate for specificity when analyzing TVS and moderate for both sensitivity and specificity in the case of MRI.

CONCLUSION:  TVS and MRI showed very similar diagnostic performance for diagnosing cervical involvement in women with endometrial cancer.

Thieme. All rights reserved.

Conflict of interest statement

The authors declare that they have no conflict of interest.

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