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Front Physiol. 2021 Feb 25;12:633093. doi: 10.3389/fphys.2021.633093. eCollection 2021.

"Urate and NOX5 Control Blood Digestion in the Hematophagous Insect .

Frontiers in physiology

Ana Caroline P Gandara, Felipe A Dias, Paula C de Lemos, Renata Stiebler, Ana Cristina S Bombaça, Rubem Menna-Barreto, Pedro L Oliveira

Affiliations

  1. Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
  2. Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.
  3. Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, Brazil.

PMID: 33716782 PMCID: PMC7947236 DOI: 10.3389/fphys.2021.633093

Abstract

Low levels of reactive oxygen species (ROS) are now recognized as essential players in cell signaling. Here, we studied the role of two conserved enzymes involved in redox regulation that play a critical role in the control of ROS in the digestive physiology of a blood-sucking insect, the kissing bug

Copyright © 2021 Gandara, Dias, de Lemos, Stiebler, Bombaça, Menna-Barreto and Oliveira.

Keywords: NADPH oxidase; ROS; Rhodnius prolixus; blood digestion; urate

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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