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Riganello F, Soddu A, Tonin P. Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness. Front Pharmacol. 2021;12:628980doi: 10.3389/fphar.2021.628980.
Riganello, F., Soddu, A., & Tonin, P. (2021). Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness. Frontiers in pharmacology, 12628980. https://doi.org/10.3389/fphar.2021.628980
Riganello, F, et al. "Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness." Frontiers in pharmacology vol. 12 (2021): 628980. doi: https://doi.org/10.3389/fphar.2021.628980
Riganello F, Soddu A, Tonin P. Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness. Front Pharmacol. 2021 Feb 17;12:628980. doi: 10.3389/fphar.2021.628980. eCollection 2021. PMID: 33679413; PMCID: PMC7926206.
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Front Pharmacol. 2021 Feb 17;12:628980. doi: 10.3389/fphar.2021.628980. eCollection 2021.

Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness.

Frontiers in pharmacology

F Riganello, A Soddu, P Tonin

Affiliations

  1. Research in Advanced NeuroRehabilitation, Istituto Sant'Anna, Crotone, Italy.
  2. Department of Physics and Astronomy, Brain and Mind Institute, Western University, London, ON, Canada.

PMID: 33679413 PMCID: PMC7926206 DOI: 10.3389/fphar.2021.628980

Abstract

Consciousness constitutes a fundamental prerequisite in the individual appraisal and experience of pain. In the same way, a person needs to be able to report on pain perception. Patients who suffered a severe brain injury with disorders of consciousness (DOC) represent a spectrum of pathologies affecting patients' capacity to interact with the external world. In these patients, the most relevant aspects in response to pain are physiologic and behavioral. The treatments and management of pain are challenging issues in these patients, arising serious ethical concerns and bringing emotional load among medical staff, caregivers, and relatives. In this review, we report the importance of having a correct pain management in DOC patients, to individuate the best pharmacological treatment that can make the difference in detecting a behavioral response, indicative of a change in the level of consciousness, and in planning a more effective rehabilitative approach.

Copyright © 2021 Riganello, Soddu and Tonin.

Keywords: assessment; disorders of consciousness; pain; pharmacotherapeutic approaches; rehabilitation

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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