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Wengert ER, Wenker IC, Wagner EL, et al. Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of . Front Neurosci. 2021;15:581048doi: 10.3389/fnins.2021.581048.
Wengert, E. R., Wenker, I. C., Wagner, E. L., Wagley, P. K., Gaykema, R. P., Shin, J. B., & Patel, M. K. (2021). Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of . Frontiers in neuroscience, 15581048. https://doi.org/10.3389/fnins.2021.581048
Wengert, Eric R, et al. "Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of ." Frontiers in neuroscience vol. 15 (2021): 581048. doi: https://doi.org/10.3389/fnins.2021.581048
Wengert ER, Wenker IC, Wagner EL, Wagley PK, Gaykema RP, Shin JB, Patel MK. Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of . Front Neurosci. 2021 Mar 04;15:581048. doi: 10.3389/fnins.2021.581048. eCollection 2021. PMID: 33762902; PMCID: PMC7982890.
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Front Neurosci. 2021 Mar 04;15:581048. doi: 10.3389/fnins.2021.581048. eCollection 2021.

Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of .

Frontiers in neuroscience

Eric R Wengert, Ian C Wenker, Elizabeth L Wagner, Pravin K Wagley, Ronald P Gaykema, Jung-Bum Shin, Manoj K Patel

Affiliations

  1. Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA, United States.
  2. Neuroscience Graduate Program, University of Virginia Health System, Charlottesville, VA, United States.
  3. Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, United States.
  4. Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, United States.

PMID: 33762902 PMCID: PMC7982890 DOI: 10.3389/fnins.2021.581048

Abstract

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death amongst patients whose seizures are not adequately controlled by current therapies. Patients with

Copyright © 2021 Wengert, Wenker, Wagner, Wagley, Gaykema, Shin and Patel.

Keywords: SCN8A encephalopathy; SUDEP; adrenergic receptors; audiogenic seizures; respiratory arrest

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. Neurobiol Dis. 2014 Sep;69:117-23 - PubMed
  2. Neurology. 2019 Jan 15;92(3):e171-e182 - PubMed
  3. Brain. 2008 Dec;131(Pt 12):3239-45 - PubMed
  4. Epilepsia. 2000 Nov;41(11):1494-7 - PubMed
  5. Neurology. 2015 Feb 3;84(5):480-9 - PubMed
  6. Sci Transl Med. 2015 Apr 8;7(282):282ra46 - PubMed
  7. Ann Neurol. 1980 Jul;8(1):1-31 - PubMed
  8. N Engl J Med. 2011 Nov 10;365(19):1801-11 - PubMed
  9. J Neurosci. 2016 Mar 2;36(9):2711-22 - PubMed
  10. Epilepsy Res. 2014 Nov;108(9):1511-8 - PubMed
  11. J Clin Invest. 2013 Apr;123(4):1798-808 - PubMed
  12. Lancet Neurol. 2016 Sep;15(10):1075-88 - PubMed
  13. Epilepsy Behav. 2017 Aug;73:6-9 - PubMed
  14. Brain. 2019 Feb 1;142(2):362-375 - PubMed
  15. J Neurosci. 2019 Apr 10;39(15):2951-2964 - PubMed
  16. J Med Genet. 2015 May;52(5):330-7 - PubMed
  17. J Neurosci. 2010 Apr 14;30(15):5167-75 - PubMed
  18. Arch Neurol. 1986 Feb;43(2):194-6 - PubMed
  19. Neurobiol Dis. 2018 Feb;110:47-58 - PubMed
  20. Br J Pharmacol Chemother. 1953 Mar;8(1):98-102 - PubMed
  21. Brain. 2018 Jun 1;141(6):1719-1733 - PubMed
  22. Epilepsia. 2019 Mar;60(3):495-507 - PubMed
  23. Neuropharmacology. 2019 Nov 1;158:107699 - PubMed
  24. Epilepsy Behav. 2019 Aug 6;:106440 - PubMed
  25. Epilepsy Res. 2018 Jul;143:79-81 - PubMed
  26. Exp Neurol. 1970 Aug;28(2):326-32 - PubMed
  27. Hypertension. 2007 Jul;50(1):6-13 - PubMed
  28. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12838-12843 - PubMed
  29. Epilepsia. 2011 Jun;52(6):1150-9 - PubMed
  30. Brain. 2019 Feb 1;142(2):412-425 - PubMed
  31. Lancet. 1999 Mar 13;353(9156):888-93 - PubMed
  32. PLoS One. 2015 Jul 23;10(7):e0133664 - PubMed
  33. Epilepsia. 2017 Sep;58(9):1637-1644 - PubMed
  34. Epilepsy Behav. 2013 Mar;26(3):415-20 - PubMed
  35. Epilepsy Behav. 2017 Jun;71(Pt B):174-180 - PubMed
  36. Exp Neurol. 1986 Mar;91(3):634-9 - PubMed
  37. J Neurosci. 2015 Jul 15;35(28):10281-9 - PubMed
  38. Front Neurol. 2019 Mar 01;10:166 - PubMed
  39. Lancet Neurol. 2013 Oct;12(10):966-77 - PubMed
  40. Epilepsia. 2010 Sep;51(9):1650-8 - PubMed
  41. Epilepsy Res. 2017 Nov;137:139-144 - PubMed
  42. Ann Otol Rhinol Laryngol. 2011 Nov;120(11):761-8 - PubMed
  43. Epilepsy Behav. 2017 Jun;71(Pt B):160-164 - PubMed
  44. Epilepsy Behav. 2011 Oct;22(2):186-90 - PubMed
  45. Am J Hum Genet. 2012 Mar 9;90(3):502-10 - PubMed
  46. Hum Mol Genet. 2015 Jan 15;24(2):506-15 - PubMed
  47. J Clin Invest. 2018 Mar 01;128(3):1141-1153 - PubMed
  48. Genes Brain Behav. 2009 Oct;8(7):699-713 - PubMed
  49. Epilepsia. 2012 Feb;53(2):227-33 - PubMed
  50. PLoS One. 2013 Oct 14;8(10):e77843 - PubMed
  51. Brain Res. 1994 Oct 17;660(2):232-40 - PubMed
  52. Epilepsia. 2014 Jul;55(7):994-1000 - PubMed
  53. Front Neurol. 2013 Jul 23;4:103 - PubMed
  54. Epilepsia. 2018 Jun;59(6):1166-1176 - PubMed
  55. J Auton Pharmacol. 1998 Jun;18(3):149-55 - PubMed
  56. Exp Neurol. 2017 Feb;288:134-141 - PubMed
  57. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4895-903 - PubMed
  58. Epilepsia. 1996 Feb;37(2):188-97 - PubMed
  59. Ann Endocrinol (Paris). 2020 Mar 18;: - PubMed
  60. Epilepsia. 1963 Mar;4:15-44 - PubMed
  61. Hear Res. 2002 Sep;171(1-2):111-118 - PubMed
  62. Epilepsy Behav. 2010 Apr;17(4):436-40 - PubMed
  63. Epilepsia. 2018 Mar;59(3):573-582 - PubMed
  64. Brain Res Dev Brain Res. 1996 Feb 26;91(2):218-26 - PubMed
  65. Exp Neurol. 2016 Jan;275 Pt 1:46-58 - PubMed
  66. Epilepsia. 2020 Feb;61(2):e13-e16 - PubMed
  67. Epilepsy Res. 2017 Sep;135:87-94 - PubMed
  68. Hear Res. 2019 Mar 15;374:1-4 - PubMed
  69. J Neurosci. 2019 Nov 27;39(48):9633-9644 - PubMed
  70. Neurology. 1972 Sep;22(9):978-87 - PubMed
  71. Neurobiol Dis. 2017 May;101:8-15 - PubMed
  72. Epilepsy Res. 2016 Aug;124:49-54 - PubMed
  73. Ann Clin Transl Neurol. 2019 Aug;6(8):1445-1455 - PubMed
  74. Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H733-40 - PubMed
  75. Fed Proc. 1985 Feb;44(2):281-9 - PubMed
  76. Neurology. 2018 Sep 18;91(12):e1112-e1124 - PubMed
  77. Pharmacopsychiatry. 2012 Sep;45(6):209-16 - PubMed
  78. J Physiol. 2014 Oct 1;592(19):4395-410 - PubMed
  79. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2383-2388 - PubMed
  80. J Neurosurg. 2019 Apr 5;132(5):1313-1323 - PubMed
  81. Epilepsy Behav. 2015 Apr;45:1-7 - PubMed
  82. Epilepsy Res. 2016 Dec;128:126-139 - PubMed
  83. Hear Res. 1995 Aug;88(1-2):143-55 - PubMed
  84. Nat Rev Neurol. 2014 May;10(5):271-82 - PubMed
  85. Epilepsia. 2020 Feb;61(2):342-349 - PubMed
  86. J Neurosci. 2017 Aug 9;37(32):7643-7655 - PubMed
  87. Epilepsy Res. 1992 Nov;13(2):95-105 - PubMed

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