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Zhang D, Zhao W, Liu J, et al. Sodium leak channel contributes to neuronal sensitization in neuropathic pain. Prog Neurobiol. 2021;202:102041doi: 10.1016/j.pneurobio.2021.102041.
Zhang, D., Zhao, W., Liu, J., Ou, M., Liang, P., Li, J., Chen, Y., Liao, D., Bai, S., Shen, J., Chen, X., Huang, H., & Zhou, C. (2021). Sodium leak channel contributes to neuronal sensitization in neuropathic pain. Progress in neurobiology, 202102041. https://doi.org/10.1016/j.pneurobio.2021.102041
Zhang, Donghang, et al. "Sodium leak channel contributes to neuronal sensitization in neuropathic pain." Progress in neurobiology vol. 202 (2021): 102041. doi: https://doi.org/10.1016/j.pneurobio.2021.102041
Zhang D, Zhao W, Liu J, Ou M, Liang P, Li J, Chen Y, Liao D, Bai S, Shen J, Chen X, Huang H, Zhou C. Sodium leak channel contributes to neuronal sensitization in neuropathic pain. Prog Neurobiol. 2021 Jul;202:102041. doi: 10.1016/j.pneurobio.2021.102041. Epub 2021 Mar 22. PMID: 33766679.
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Prog Neurobiol. 2021 Jul;202:102041. doi: 10.1016/j.pneurobio.2021.102041. Epub 2021 Mar 22.

Sodium leak channel contributes to neuronal sensitization in neuropathic pain.

Progress in neurobiology

Donghang Zhang, Wenling Zhao, Jin Liu, Mengchan Ou, Peng Liang, Jia Li, Yali Chen, Daqing Liao, Siqi Bai, Jiefei Shen, Xiangdong Chen, Han Huang, Cheng Zhou

Affiliations

  1. Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China; Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
  2. Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
  3. Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
  4. Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases and Department of Prosthodontics, West China Stomatology Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
  5. Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.
  6. Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China; Department of Anesthesiology & Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second Hospital of Sichuan University, Chengdu 610041, Sichuan, China. Electronic address: [email protected].
  7. Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China; Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China. Electronic address: [email protected].

PMID: 33766679 DOI: 10.1016/j.pneurobio.2021.102041

Abstract

Neuropathic pain affects up to 10 % of the total population and no specific target is ideal for therapeutic need. The sodium leak channel (NALCN), a non-selective cation channel, mediates the background Na

Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords: Dorsal root ganglion; Dorsal spinal cord; Neuronal sensitization; Neuropathic pain; Sodium leak channel

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