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Urology. 2021 Aug;154:227-232. doi: 10.1016/j.urology.2021.03.016. Epub 2021 Mar 27.

Environmental Safety of the 180-W GreenLight Laser: A Pilot Study On Plume And Irrigating Fluids.

Urology

Giovanni Ferrari, Anna Maria Ferrari, Davide Campobasso, Alberto Modenese, Enrique Rijo, Vincent Misrai, Roberto Rosa, Luca Cindolo

Affiliations

  1. Department of Urology, Hesperia Hospital, CURE Group, Modena, Italy.
  2. Department of Sciences and Methods for Engineering, University of Modena and Reggio Emilia, Reggio Emilia, Italy.
  3. Department of Urology, Ospedale Civile di Guastalla ed Ospedale Ercole Franchini di Montecchio Emilia, Azienda USL-IRCCS di Reggio Emilia, Italy.
  4. Department of Biomedical, Metabolic and Neural Sciences, University of Modena & Reggio Emilia, Modena, Italy.
  5. Department of Urology, Hospital Quiron Barcelona, Barcelona, Spain.
  6. Department of Urology, Pasteur Clinic, Toulouse, France.

PMID: 33785403 DOI: 10.1016/j.urology.2021.03.016

Abstract

OBJECTIVE: To analyze the chemical composition of the surgical smoke and the outflow irrigation fluid produced during a common endourological surgical procedure to treat benign prostatic obstruction (BPO).

METHODS: A prospective study was performed to analyze the surgical smoke generated during photoselective vaporization of the prostate (PVP) using the 180-W GL-XPS GreenLight Laser system. Surgical smoke samples were collected from 5 patients, and irrigation fluid samples were collected from 5 different patients. Qualitative organic compound determination was performed on both types of collected specimens using headspace-gas chromatography/mass spectrometry (HS-GC/MS) analysis.

RESULTS: Four organic compounds were identified in the analyses of the smoke samples: tetradecane, hexadecane, 7-methylpentadecane and 2,6-dimethyleptadecane. In the analysis of fluid samples, 16 organic elements were identified. Interestingly, two compounds present in the first group (7-methylpentadecane and 2,6-dimethyleptadecane) were not detected in the fluid samples from the second group. None of the sixteen compounds detected in the fluids were present in all of the samples. Overall, seven of these compounds can be classified as toxic for acute exposure, while 4 others may represent a health hazard.

CONCLUSION: We found that the different types of surgical smoke and irrigation fluids produced during PVP with a GreenLight Laser contain a limited number of organic compounds with a potential inhalation hazard. More studies are needed to understand the potential hazard for the exposed employees.

Copyright © 2021 Elsevier Inc. All rights reserved.

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