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Hum Reprod Open. 2021 Mar 21;2021(1):hoab009. doi: 10.1093/hropen/hoab009. eCollection 2021.

A global approach to addressing the policy, research and social challenges of male reproductive health.

Human reproduction open

Christopher L R Barratt, Christopher J De Jonge, Richard A Anderson, Michael L Eisenberg, Nicolás Garrido, Satu Rautakallio Hokkanen, Csilla Krausz, Sarah Kimmins, Moira K O'Bryan, Allan A Pacey, Frank Tüttelmann, Joris A Veltman

Affiliations

  1. Division of Systems Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
  2. Department of Urology, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA.
  3. Section of Obstetrics and Gynaecology, MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, UK.
  4. Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.
  5. IVI Foundation, Health Research Institute La Fe, Valencia, Spain.
  6. Chair, Fertility Europe, Belgium.
  7. Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy.
  8. Department of Pharmacology and Therapeutics, Faculty of Medicine, McGill University, and Department of Animal Science, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, Canada.
  9. Department of Anatomy and Developmental Biology, School of BioSciences, Faculty of Science, University of Melbourne, Parkville, Australia.
  10. Department of Oncology & Metabolism, University of Sheffield, Sheffield, UK.
  11. Institute of Reproductive Genetics, University of Münster, Münster, Germany.
  12. Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

PMID: 33768166 PMCID: PMC7982782 DOI: 10.1093/hropen/hoab009

Abstract

Male infertility is a global health issue; yet to a large extent, our knowledge of its causes, impact and consequence is largely unknown. Recent data indicate that infertile men have an increased risk of somatic disorders such as cancer and die younger compared to fertile men. Moreover, several studies point to a significant adverse effect on the health of the offspring. From the startling lack of progress in male contraception combined with the paucity of improvements in the diagnosis of male infertility, we conclude there is a crisis in male reproductive health. The Male Reproductive Health Initiative has been organized to directly address these issues (www.eshre.eu/Specialty-groups/Special-Interest-Groups/Andrology/MRHI). The Working Group will formulate an evidence-based strategic road map outlining the ways forward. This is an open consortium desiring to engage with all stakeholders and governments.

© The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

Keywords: male contraception; male infertility; male reproductive health initiative; policy; research; society

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