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Spoulou V, Noni M, Koukou D, et al. Clinical characteristics of COVID-19 in neonates and young infants. Eur J Pediatr. 2021;180(9):3041-3045doi: 10.1007/s00431-021-04042-x.
Spoulou, V., Noni, M., Koukou, D., Kossyvakis, A., & Michos, A. (2021). Clinical characteristics of COVID-19 in neonates and young infants. European journal of pediatrics, 180(9), 3041-3045. https://doi.org/10.1007/s00431-021-04042-x
Spoulou, Vana, et al. "Clinical characteristics of COVID-19 in neonates and young infants." European journal of pediatrics vol. 180,9 (2021): 3041-3045. doi: https://doi.org/10.1007/s00431-021-04042-x
Spoulou V, Noni M, Koukou D, Kossyvakis A, Michos A. Clinical characteristics of COVID-19 in neonates and young infants. Eur J Pediatr. 2021 Sep;180(9):3041-3045. doi: 10.1007/s00431-021-04042-x. Epub 2021 Mar 31. PMID: 33786658; PMCID: PMC8009690.
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Eur J Pediatr. 2021 Sep;180(9):3041-3045. doi: 10.1007/s00431-021-04042-x. Epub 2021 Mar 31.

Clinical characteristics of COVID-19 in neonates and young infants.

European journal of pediatrics

Vana Spoulou, Maria Noni, Dimitra Koukou, Athanasios Kossyvakis, Athanasios Michos

Affiliations

  1. 1st Department of Pediatrics, "Aghia Sophia" Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece. [email protected].
  2. 1st Department of Pediatrics, "Aghia Sophia" Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  3. National Reference Laboratory for Influenza and other Respiratory Viruses, Hellenic Pasteur Institute, Athens, Greece.

PMID: 33786658 PMCID: PMC8009690 DOI: 10.1007/s00431-021-04042-x

Abstract

We report the clinical characteristics and management of fourteen neonates and very young infants with COVID-19. Although all presented with mild symptoms and did not require specific treatment, most of them had abnormal laboratory and radiological findings. Ten infants presented with neutropenia and/or monocytosis but none with lymphopenia. Transient hypertriglyceridemia and/or prolonged viral shedding were detected in 9 patients.Conclusion: Based to our experience, COVID-19 is mild in very young infants and might have distinct laboratory findings. What is Known: • SARS-CoV-2 in infants is a mild disease. • The period of transmission is approximately 2 weeks. What is New: • Very young age is not a risk factor for severe COVID-19 but could be associated with prolonged viral shedding. • Neutropenia and monocytosis are distinct characteristics of COVID-19 in very young infants.

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Keywords: COVID-19; Infants; Pandemic; SARS-CoV-2

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