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Evid Based Complement Alternat Med. 2021 Feb 22;2021:8858165. doi: 10.1155/2021/8858165. eCollection 2021.

[No title available]

Evidence-based complementary and alternative medicine : eCAM

Bruno M Moukette, José P Castelão-Baptista, Luciana Ferreira, Ana M Silva, Rui F Simões, Célia Cabral, Constant A Pieme, Jeanne Y Ngogang, Vilma A Sardão, Paulo J Oliveira

Affiliations

  1. Laboratory of Biochemistry, Department of Biochemistry and Physiological Sciences, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon.
  2. CNC-Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech Building, Lot 8A, Biocant Park, Cantanhede 3060-197, Portugal.
  3. Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, Coimbra, Portugal.
  4. University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra 3000-548, Portugal.
  5. University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Clinic Academic Center of Coimbra (CACC), Faculty of Medicine, Coimbra 3000-548, Portugal.

PMID: 33688366 PMCID: PMC7920721 DOI: 10.1155/2021/8858165

Abstract

MATERIALS AND METHODS: Bark extracts of these plants (1 and 25 

RESULTS: The results confirmed that Dox treatment decreased cell mass, mitochondrial membrane potential and metabolic viability, increased mitochondrial superoxide anion, and stimulated caspase-3 and caspase-9-like activities. Pretreatment of the cells with the plant extracts significantly inhibited Dox cytotoxicity, with more significant results at the higher concentration. Measurements of selenium and vitamin C in the extracts revealed higher concentration of both when compared with other Cameroonian spices.

CONCLUSION: Both extracts of

Copyright © 2021 Bruno M. Moukette et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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