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Bordejevic DA, Pârvănescu T, Petrescu L, et al. Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania. Ther Clin Risk Manag. 2021;17:249-258doi: 10.2147/TCRM.S295251.
Bordejevic, D. A., Pârvănescu, T., Petrescu, L., Mornoș, C., Olariu, I., Crișan, S., Văcărescu, C., Lazăr, M., Morariu, V. I., Citu, I. M., Tomescu, M. C., & Cozma, D. (2021). Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania. Therapeutics and clinical risk management, 17249-258. https://doi.org/10.2147/TCRM.S295251
Bordejevic, Diana Aurora, et al. "Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania." Therapeutics and clinical risk management vol. 17 (2021): 249-258. doi: https://doi.org/10.2147/TCRM.S295251
Bordejevic DA, Pârvănescu T, Petrescu L, Mornoș C, Olariu I, Crișan S, Văcărescu C, Lazăr M, Morariu VI, Citu IM, Tomescu MC, Cozma D. Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania. Ther Clin Risk Manag. 2021 Mar 23;17:249-258. doi: 10.2147/TCRM.S295251. eCollection 2021. PMID: 33790565; PMCID: PMC8001577.
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Ther Clin Risk Manag. 2021 Mar 23;17:249-258. doi: 10.2147/TCRM.S295251. eCollection 2021.

Left Ventricular Remodeling Risk Predicted by Two-Dimensional Speckle Tracking Echocardiography in Acute Myocardial Infarction Patients with Midrange or Preserved Ejection Fraction in Western Romania.

Therapeutics and clinical risk management

Diana Aurora Bordejevic, Tudor Pârvănescu, Lucian Petrescu, Cristian Mornoș, Ioan Olariu, Simina Crișan, Cristina Văcărescu, Mihai Lazăr, Vlad Ioan Morariu, Ioana Mihaela Citu, Mirela Cleopatra Tomescu, Dragoș Cozma

Affiliations

  1. Cardiology Department, Institute of Cardiovascular Diseases, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
  2. Cardiology Department, City Hospital, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

PMID: 33790565 PMCID: PMC8001577 DOI: 10.2147/TCRM.S295251

Abstract

BACKGROUND: Patients with acute myocardial infarction (AMI) are at high risk for left ventricular (LV) remodeling and heart failure. We aimed to study whether LV strains (S) and strain rates (SR) could predict cardiac remodeling in patients with AMI having a midrange or preserved LV ejection fraction (EF) following a percutaneous coronary intervention (PCI) within the first 12 hours from the onset of symptoms.

PATIENTS AND METHODS: This is a case-control observational study including patients admitted for their first AMI, either with ST-segment elevation (STEMI) or without ST elevation (NSTEMI), with an LVEF > 40% after a successful PCI. Echocardiography was repeated after 6 months, and the patients were divided into two groups, according to whether LV remodeling was determined on echocardiography.

RESULTS: Of the 253 AMI patients (mean 66 aged ± 13 years), including 185 males (73%), 61 (24%) presented signs of LV remodeling. In univariate logistic regression analysis, age, male sex, smoking history, hypertension, hypercholesterolemia, Killip class, renal function, peak creatine phosphokinase - MB level, 2- and 3-vessel coronary artery disease (CAD), and several echocardiographic parameters were significantly associated with LV remodeling (

CONCLUSION: We concluded that 2D-STE was the best method to evaluate LV remodeling in patients with AMI and midrange or preserved LVEF following myocardial revascularization by a PCI.

© 2021 Bordejevic et al.

Keywords: 2D speckle tracking echocardiography; AMI; LV remodeling; PCI; midrange LVEF; preserved LVEF

Conflict of interest statement

The authors report no conflicts of interest in this work.

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