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Ind Psychiatry J. 2020 Jan-Jun;29(1):105-122. doi: 10.4103/ipj.ipj_70_20. Epub 2020 Nov 07.

Neuropsychological dysfunctions among chronic schizophrenia patients, alcohol dependence cases, and normal subjects: A comparative study.

Industrial psychiatry journal

Vidhata Dixit, Santosh Kumar, Suprakash Chaudhury

Affiliations

  1. Department of Clinical Psychology, RINPAS, Ranchi, Jharkhand, India.
  2. Department of Psychiatry, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
  3. Department of Psychiatry, Dr. D. Y. Patil Medical College, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.

PMID: 33776284 PMCID: PMC7989451 DOI: 10.4103/ipj.ipj_70_20

Abstract

AIM: The aim of this study is to assess the neuropsychological profiles of chronic schizophrenia and alcohol-dependent subjects.

MATERIALS AND METHODS: This hospital-based cross-sectional study included 30 chronic schizophrenia patients, 30 alcohol-dependent patients and 30-matched normal controls. Demographic and clinical data were collected on a self-designed pro forma. Positive and Negative Syndrome Scale (PANSS) and Severity of Alcohol Dependence Questionnaire (SADQ-C) were administered to chronic schizophrenia and alcohol-dependent patients, respectively. The AIIMS Comprehensive Neuropsychological Battery in Hindi (Adult Form) was used to assess neuropsychological dysfunctions.

RESULTS: Neuropsychological dysfunctions were found in 83.3% of chronic schizophrenia patients, 36.7% alcohol dependents and none of the normal subjects. In comparison to normal subjects, schizophrenia patients had significantly more dysfunctions in neuropsychological-domains such as motor, tactile, visual, receptive and expressive speech, reading, writing, arithmetic, memory, and intellectual processes. A significant positive correlation was found between the PANSS total score and

CONCLUSIONS: Neuropsychological dysfunction was significantly more common and severe in chronic schizophrenia patients than in alcohol-dependent patients. In comparison to alcohol dependents, the chronic schizophrenia patients had more dysfunctions in neuropsychological-domains such as tactile, arithmetic, memory, and intellectual processes.

Copyright: © 2020 Industrial Psychiatry Journal.

Keywords: Alcohol dependence; psychopathology; reading; schizophrenia; speech; writing

Conflict of interest statement

There are no conflicts of interest.

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