Ind Psychiatry J. 2020 Jan-Jun;29(1):105-122. doi: 10.4103/ipj.ipj_70_20. Epub 2020 Nov 07.
Neuropsychological dysfunctions among chronic schizophrenia patients, alcohol dependence cases, and normal subjects: A comparative study.
Industrial psychiatry journal
Vidhata Dixit, Santosh Kumar, Suprakash Chaudhury
Affiliations
Affiliations
- Department of Clinical Psychology, RINPAS, Ranchi, Jharkhand, India.
- Department of Psychiatry, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
- Department of Psychiatry, Dr. D. Y. Patil Medical College, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.
PMID: 33776284
PMCID: PMC7989451 DOI: 10.4103/ipj.ipj_70_20
Abstract
AIM: The aim of this study is to assess the neuropsychological profiles of chronic schizophrenia and alcohol-dependent subjects.
MATERIALS AND METHODS: This hospital-based cross-sectional study included 30 chronic schizophrenia patients, 30 alcohol-dependent patients and 30-matched normal controls. Demographic and clinical data were collected on a self-designed pro forma. Positive and Negative Syndrome Scale (PANSS) and Severity of Alcohol Dependence Questionnaire (SADQ-C) were administered to chronic schizophrenia and alcohol-dependent patients, respectively. The AIIMS Comprehensive Neuropsychological Battery in Hindi (Adult Form) was used to assess neuropsychological dysfunctions.
RESULTS: Neuropsychological dysfunctions were found in 83.3% of chronic schizophrenia patients, 36.7% alcohol dependents and none of the normal subjects. In comparison to normal subjects, schizophrenia patients had significantly more dysfunctions in neuropsychological-domains such as motor, tactile, visual, receptive and expressive speech, reading, writing, arithmetic, memory, and intellectual processes. A significant positive correlation was found between the PANSS total score and
CONCLUSIONS: Neuropsychological dysfunction was significantly more common and severe in chronic schizophrenia patients than in alcohol-dependent patients. In comparison to alcohol dependents, the chronic schizophrenia patients had more dysfunctions in neuropsychological-domains such as tactile, arithmetic, memory, and intellectual processes.
Copyright: © 2020 Industrial Psychiatry Journal.
Keywords: Alcohol dependence; psychopathology; reading; schizophrenia; speech; writing
Conflict of interest statement
There are no conflicts of interest.
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