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Alvisi N, van Noort K, Dwiani S, et al. β-Hexosaminidases Along the Secretory Pathway of . Front Plant Sci. 2021;12:638454doi: 10.3389/fpls.2021.638454.
Alvisi, N., van Noort, K., Dwiani, S., Geschiere, N., Sukarta, O., Varossieau, K., Nguyen, D. L., Strasser, R., Hokke, C. H., Schots, A., & Wilbers, R. H. P. (2021). β-Hexosaminidases Along the Secretory Pathway of . Frontiers in plant science, 12638454. https://doi.org/10.3389/fpls.2021.638454
Alvisi, Nicolò, et al. "β-Hexosaminidases Along the Secretory Pathway of ." Frontiers in plant science vol. 12 (2021): 638454. doi: https://doi.org/10.3389/fpls.2021.638454
Alvisi N, van Noort K, Dwiani S, Geschiere N, Sukarta O, Varossieau K, Nguyen DL, Strasser R, Hokke CH, Schots A, Wilbers RHP. β-Hexosaminidases Along the Secretory Pathway of . Front Plant Sci. 2021 Mar 17;12:638454. doi: 10.3389/fpls.2021.638454. eCollection 2021. PMID: 33815445; PMCID: PMC8010188.
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Front Plant Sci. 2021 Mar 17;12:638454. doi: 10.3389/fpls.2021.638454. eCollection 2021.

β-Hexosaminidases Along the Secretory Pathway of .

Frontiers in plant science

Nicolò Alvisi, Kim van Noort, Sarlita Dwiani, Nathan Geschiere, Octavina Sukarta, Koen Varossieau, Dieu-Linh Nguyen, Richard Strasser, Cornelis H Hokke, Arjen Schots, Ruud H P Wilbers

Affiliations

  1. Laboratory of Nematology, Plant Sciences Group, Wageningen University and Research, Wageningen, Netherlands.
  2. Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
  3. Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.

PMID: 33815445 PMCID: PMC8010188 DOI: 10.3389/fpls.2021.638454

Abstract

Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases. Yet, the identification of single molecules that can be developed into novel biopharmaceuticals is hampered by the limited availability of native parasite-derived proteins. Recently, pioneering work has shown that helminth glycoproteins can be produced transiently in

Copyright © 2021 Alvisi, van Noort, Dwiani, Geschiere, Sukarta, Varossieau, Nguyen, Strasser, Hokke, Schots and Wilbers.

Keywords: LacdiNAc; N-glycosylation; Nicotiana benthamiana; glyco-engineering; β-hexosaminidases

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. Parasite Immunol. 1999 Apr;21(4):169-76 - PubMed
  2. Int J Parasitol. 2018 Apr;48(5):371-378 - PubMed
  3. PLoS One. 2012;7(10):e46460 - PubMed
  4. Immunity. 2018 Nov 20;49(5):801-818 - PubMed
  5. Plant Biotechnol J. 2008 May;6(4):392-402 - PubMed
  6. J Biol Chem. 2012 Apr 6;287(15):11911-23 - PubMed
  7. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2899-904 - PubMed
  8. Sci Rep. 2020 Oct 28;10(1):18528 - PubMed
  9. Inflamm Bowel Dis. 2008 May;14(5):709-20 - PubMed
  10. Am J Physiol Gastrointest Liver Physiol. 2003 Mar;284(3):G385-91 - PubMed
  11. J Biol Chem. 2006 Feb 24;281(8):4867-75 - PubMed
  12. Biochimie. 2014 Dec;107 Pt B:263-9 - PubMed
  13. Plant Biotechnol J. 2017 Feb;15(2):197-206 - PubMed
  14. Plant Biotechnol J. 2019 Feb;17(2):350-361 - PubMed
  15. Mol Cell Proteomics. 2011 May;10(5):M110.005710 - PubMed
  16. J Immunol. 2006 Jan 1;176(1):138-47 - PubMed
  17. J Biol Chem. 2012 Oct 19;287(43):36518-26 - PubMed
  18. Front Bioeng Biotechnol. 2018 Jun 14;6:81 - PubMed
  19. Immunity. 2014 Jun 19;40(6):833-42 - PubMed
  20. Ann N Y Acad Sci. 2012 Apr;1253:E1-E13 - PubMed
  21. MAbs. 2016 Nov/Dec;8(8):1456-1466 - PubMed
  22. Biotechnol Bioeng. 2019 Oct;116(10):2526-2539 - PubMed
  23. Plant Biotechnol J. 2016 Feb;14(2):670-81 - PubMed
  24. FASEB J. 2015 Jul;29(7):3027-39 - PubMed
  25. J Exp Med. 2012 Sep 24;209(10):1753-67, S1 - PubMed
  26. Curr Pharm Des. 2013;19(31):5503-12 - PubMed
  27. Parasite Immunol. 2014 Sep;36(9):439-52 - PubMed
  28. Annu Rev Plant Biol. 2014;65:743-68 - PubMed
  29. Int Immunol. 2003 Jan;15(1):59-69 - PubMed
  30. J Biol Chem. 2011 Mar 25;286(12):10793-802 - PubMed
  31. Glycobiology. 2011 Jun;21(6):813-23 - PubMed
  32. BMC Immunol. 2015 Mar 26;16:12 - PubMed
  33. Immunotargets Ther. 2015 Jul 27;4:143-57 - PubMed
  34. Carbohydr Res. 2009 Aug 17;344(12):1487-93 - PubMed
  35. PLoS One. 2011;6(10):e26040 - PubMed
  36. Plant Physiol. 2014 Dec;166(4):1839-51 - PubMed
  37. J Biol Chem. 2007 Sep 21;282(38):27825-40 - PubMed
  38. Parasite Immunol. 2005 Jul-Aug;27(7-8):257-64 - PubMed
  39. Sci Rep. 2017 Apr 10;7:45910 - PubMed
  40. Plant Cell. 2004 Sep;16(9):2529-40 - PubMed
  41. FASEB J. 2021 Feb;35(2):e21331 - PubMed
  42. J Biol Chem. 1995 Jul 21;270(29):17344-9 - PubMed
  43. Lancet. 2006 Aug 26;368(9537):733-43 - PubMed
  44. Glycobiology. 2015 Apr;25(4):448-64 - PubMed
  45. Mol Biochem Parasitol. 2017 Jul;215:47-57 - PubMed
  46. Mol Plant Microbe Interact. 2012 Dec;25(12):1523-30 - PubMed
  47. Plant Physiol. 2007 Sep;145(1):5-16 - PubMed
  48. Int J Parasitol. 2018 Apr;48(5):359-369 - PubMed
  49. Immunol Rev. 2014 May;259(1):206-30 - PubMed
  50. Lancet. 2009 Jun 13;373(9680):2027-33 - PubMed

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