Display options
Share it on

Evid Based Complement Alternat Med. 2021 Mar 17;2021:5557667. doi: 10.1155/2021/5557667. eCollection 2021.

Comparison of Ethanolic and Aqueous-Polyethylenglycolic Propolis Extracts: Chemical Composition and Antioxidant Properties.

Evidence-based complementary and alternative medicine : eCAM

Mindaugas Liaudanskas, Loreta Kubilienė, Vaidotas Žvikas, Sonata Trumbeckaitė

Affiliations

  1. Department of Pharmacognosy, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukil?li? Av. 13, LT-50162 Kaunas, Lithuania.
  2. Institute of Pharmaceutical Technologies, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukil?li? Av. 13, LT-50162 Kaunas, Lithuania.
  3. Department of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukil?li? Av. 13, LT-50162 Kaunas, Lithuania.
  4. Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Sukil?li? Av. 13, LT-50162 Kaunas, Lithuania.

PMID: 33815551 PMCID: PMC7994069 DOI: 10.1155/2021/5557667

Abstract

In recent years, particular attention has been paid to the natural antioxidants. Bee products, especially propolis, are characterized by multifunctional (antioxidant, anti-inflammatory, antibacterial, antiviral, and food preservative) effects and can be used for the development of functional food or food preservatives. Propolis extracts that are commonly produced are ethanolic; therefore, to certain groups of consumers, for example, children and alcohol sensitive group, their applicability is limited. The aim of this study was to develop alternative propolis from aqueous-polyethylenglycolic propolis extract (AQUA-PEG) and compare the chemical composition as well as antioxidant (radical-scavenging and reduction properties) activities to those of ethanolic propolis extract (EEP). Polyethylene glycol is quite a good solvent, which can be successfully used for the preparation of NEP. The total quantity of phenolic compounds identified in AQUA-PEG (400.36 

Copyright © 2021 Mindaugas Liaudanskas et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

References

  1. Curr Pharm Des. 2018;24(2):146-157 - PubMed
  2. Environ Toxicol Pharmacol. 2015 Nov;40(3):901-6 - PubMed
  3. Daru. 2019 Jun;27(1):433-449 - PubMed
  4. Int J Mol Sci. 2018 May 25;19(6): - PubMed
  5. Environ Sci Pollut Res Int. 2019 Aug;26(24):24672-24682 - PubMed
  6. J Ethnopharmacol. 2005 Sep 14;100(3):276-83 - PubMed
  7. Molecules. 2007 Jul 19;12(7):1496-547 - PubMed
  8. Molecules. 2019 Jan 21;24(2): - PubMed
  9. Z Naturforsch C J Biosci. 2000 Jan-Feb;55(1-2):70-5 - PubMed
  10. Front Microbiol. 2019 Apr 18;10:829 - PubMed
  11. J Food Drug Anal. 2018 Oct;26(4):1293-1302 - PubMed
  12. Anal Biochem. 1996 Jul 15;239(1):70-6 - PubMed
  13. Fundam Clin Pharmacol. 2003 Feb;17(1):93-102 - PubMed
  14. Nutrients. 2019 May 09;11(5): - PubMed
  15. Nutr Metab Insights. 2019 Oct 21;12:1178638819882739 - PubMed
  16. Free Radic Biol Med. 1999 May;26(9-10):1231-7 - PubMed
  17. Antioxidants (Basel). 2019 May 18;8(5): - PubMed
  18. Curr Med Chem. 2012;19(18):2876-900 - PubMed
  19. Phytother Res. 2010 Jan;24 Suppl 1:S20-8 - PubMed
  20. J Agric Food Chem. 2005 May 18;53(10):4290-302 - PubMed
  21. BMC Complement Altern Med. 2015 May 27;15:156 - PubMed
  22. Medicines (Basel). 2018 Jan 03;5(1): - PubMed
  23. Pharmacol Biochem Behav. 2008 Sep;90(3):441-6 - PubMed

Publication Types