Display options
Cite
Vernaci GM, Meroni M, Dieci MV, et al. Postsurgical Pyoderma Gangrenosum in a Breast Cancer Patient: A Case Report and Literature Review. Case Rep Oncol. 2021;14(1):160-164doi: 10.1159/000509745.
Vernaci, G. M., Meroni, M., Dieci, M. V., Saibene, T., Montesco, M. C., Orvieto, E., Cattelan, A., Ghiotto, C., Miglietta, F., Guarneri, V., & Cagol, M. (2021). Postsurgical Pyoderma Gangrenosum in a Breast Cancer Patient: A Case Report and Literature Review. Case reports in oncology, 14(1), 160-164. https://doi.org/10.1159/000509745
Vernaci, Grazia Maria, et al. "Postsurgical Pyoderma Gangrenosum in a Breast Cancer Patient: A Case Report and Literature Review." Case reports in oncology vol. 14,1 (2021): 160-164. doi: https://doi.org/10.1159/000509745
Vernaci GM, Meroni M, Dieci MV, Saibene T, Montesco MC, Orvieto E, Cattelan A, Ghiotto C, Miglietta F, Guarneri V, Cagol M. Postsurgical Pyoderma Gangrenosum in a Breast Cancer Patient: A Case Report and Literature Review. Case Rep Oncol. 2021 Mar 01;14(1):160-164. doi: 10.1159/000509745. eCollection 2021. PMID: 33776698; PMCID: PMC7983549.
Copy Download .nbib Format: NLM
Share it on

Case Rep Oncol. 2021 Mar 01;14(1):160-164. doi: 10.1159/000509745. eCollection 2021.

Postsurgical Pyoderma Gangrenosum in a Breast Cancer Patient: A Case Report and Literature Review.

Case reports in oncology

Grazia Maria Vernaci, Muzio Meroni, Maria Vittoria Dieci, Tania Saibene, Maria Cristina Montesco, Enrico Orvieto, Annamaria Cattelan, Cristina Ghiotto, Federica Miglietta, Valentina Guarneri, Matteo Cagol

Affiliations

  1. Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
  2. Division of Medical Oncology 2, Istituto Oncologico Veneto IRCCS, Padua, Italy.
  3. Anaesthesiology Unit, Istituto Oncologico Veneto IRCCS, Padua, Italy.
  4. Breast Surgery Unit, Istituto Oncologico Veneto IRCCS, Padua, Italy.
  5. Anatomy and Histology Unit, Istituto Oncologico Veneto IRCCS, Padua, Italy.
  6. Department of Pathology, Azienda Ospedaliera di Rovigo, Rovigo, Italy.
  7. Unit of Infectious Disease, Department of Internal Medicine, Azienda Ospedaliera Universitaria di Padova, Padua, Italy.

PMID: 33776698 PMCID: PMC7983549 DOI: 10.1159/000509745

Abstract

Pyoderma gangrenosum is a rare skin necrotizing disease that can arise on a site of surgical trauma. Its pathogenesis has recently been related to dysregulation of the immune system, with inflammatory bowel disease representing the most commonly underlying systemic conditions. Several authors have also reported an association with solid malignancies (especially gastrointestinal and breast cancer). We describe the case of a 39-year-old patient diagnosed with a locally advanced, triple-negative breast cancer who developed a pyoderma gangrenosum on the surgical wound after a CVC implant with systemic complications. As the diagnosis and management of postsurgical pyoderma gangrenosum can be challenging for clinicians, underlying conditions as autoimmune disease and solid tumors have to be considered in order to guide treatment.

Copyright © 2021 by S. Karger AG, Basel.

Keywords: Breast cancer; Pathergy; Pyoderma gangrenosum; Solid tumors

Conflict of interest statement

The authors declare that they have no conflict of interest.

References

  1. J Dtsch Dermatol Ges. 2016 Oct;14(10):1023-1030 - PubMed
  2. Am J Clin Dermatol. 2012 Jun 1;13(3):191-211 - PubMed
  3. J Eur Acad Dermatol Venereol. 2009 Sep;23(9):1008-17 - PubMed
  4. Int J Dermatol. 2013 Aug;52(8):938-45 - PubMed
  5. J Med Case Rep. 2014 Jun 25;8:226 - PubMed
  6. Arch Dermatol. 1989 Jan;125(1):57-64 - PubMed
  7. Int J Dermatol. 2015 Sep;54(9):e351-7 - PubMed
  8. J Plast Reconstr Aesthet Surg. 2017 Jul;70(7):884-892 - PubMed
  9. J Dermatol. 2015 Jun;42(6):650-1 - PubMed

Publication Types