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North Clin Istanb. 2021 Mar 22;8(2):119-123. doi: 10.14744/nci.2021.60420. eCollection 2021.

ICU admission rates in Istanbul following the addition of favipiravir to the national COVID-19 treatment protocol.

Northern clinics of Istanbul

Abdullah Emre Guner, Aral Surmeli, Kemal Kural, Habip Yilmaz, Erdogan Kocayigit, Esra Sahin, Perihan Alkan, Cemal Kazezoglu, Serdal Zelyurt, Kemal Memisoglu, Isil Maral

Affiliations

  1. Istanbul Health Directorate, Public Health Services, Istanbul, Turkey.
  2. Medical Rescue Association of Turkey, Istanbul, Turkey.
  3. Istanbul Health Directorate, Monitoring, Evaluation and Statistics, Istanbul, Turkey.
  4. Istanbul Health Directorate, Department of Public Hospital Services, Istanbul, Turkey.
  5. Istanbul Health Directorate, Infectious Diseases, Istanbul, Turkey.
  6. Health Sciences University, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey.
  7. Istanbul Health Directorate, Support Services, Istanbul, Turkey.
  8. Istanbul Health Directorate, Director of Health, Istanbul, Turkey.
  9. Department of Public Health, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Turkey.

PMID: 33851074 PMCID: PMC8039109 DOI: 10.14744/nci.2021.60420

Abstract

OBJECTIVE: The objective of this study was to understand the observational relationship between adoption of favipiravir into the national COVID-19 treatment protocol and intensive care unit (ICU) admission rates in Istanbul due to COVID-19.

METHODS: Data were harvested from the "Public Health Management System-HSYS," which collate centrally the records of all known cases of COVID-19. The total number of cases, numbers admitted to ICU, and number undergoing intubation were compared between 2 time periods: 11

RESULTS: The percentage of patients requiring ICU admission diminished from 24% to 12%, whilst the percentage intubated fell from 77% to 66%. These differences were both statistically significant.

CONCLUSION: The addition of favipiravir to the national COVID-19 treatment protocol may explain this rapid decrease in the rate of ICU admissions and intubation.

Copyright: © 2021 by Istanbul Northern Anatolian Association of Public Hospitals.

Keywords: COVID-19; favipiravir; intensive care unit

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

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