Display options
Share it on

Case Rep Cardiol. 2021 Mar 27;2021:2806193. doi: 10.1155/2021/2806193. eCollection 2021.

Symptomatic Supraventricular Tachycardia Resistant to Adenosine Therapy in a Patient with Chronic Theophylline Use.

Case reports in cardiology

Seyedeh Maryam Hosseini, Muhammad Ajmal, Ranjith Shetty

Affiliations

  1. University of Arizona College of Medicine, USA.
  2. Carondelet Medical Group, USA.

PMID: 33854801 PMCID: PMC8019626 DOI: 10.1155/2021/2806193

Abstract

Theophylline is a potent adenosine receptor antagonist with indirect adrenergic effects that can lead to arrhythmias and metabolic abnormalities such as hypokalemia. Therapeutic toxicity cases have declined over the years mainly due to decreased recommended therapeutic doses and overall decreased usage of this medication due to newer available COPD treatment options. We present a clinical case of symptomatic supraventricular tachycardia resistant to adenosine therapy in a patient with theophylline use. This case highlights the importance of comprehensive medication review in acute settings to aid in identifying the underlying etiologies and initiating prompt treatments. It also signifies the importance of reviewing chronic medications in each outpatient visits to ensure continued indication for their use and be able to change them to newer agents per guidelines whenever possible.

Copyright © 2021 Seyedeh Maryam Hosseini et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

References

  1. West J Med. 1984 Oct;141(4):485-90 - PubMed
  2. Ann Intern Med. 1993 Dec 15;119(12):1161-7 - PubMed
  3. J Toxicol Clin Toxicol. 1994;32(1):41-7 - PubMed
  4. Ann Emerg Med. 1991 Jul;20(7):717-21 - PubMed
  5. Am J Emerg Med. 1996 Oct;14(6):606-12 - PubMed
  6. Eur J Med Res. 1998 Aug 18;3(8):380-2 - PubMed
  7. Am J Respir Crit Care Med. 2013 Oct 15;188(8):901-6 - PubMed

Publication Types