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Biomedicine (Taipei). 2020 Jun 05;10(2):12-22. doi: 10.37796/2211-8039.1025. eCollection 2020.

Cyclohexylamine, an active compound from .

BioMedicine

Yuh-Fung Chen, Yu-Wen Wang, Ih-Sheng Chen, Huei-Yann Tsai

Affiliations

  1. Department of Pharmacology, China Medical University, Taichung, Taiwan.
  2. School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
  3. Department of Pharmacy, China Medical University Hospital, Taichung, Taiwan.

PMID: 33854916 PMCID: PMC7608847 DOI: 10.37796/2211-8039.1025

Abstract

METHODS: Male S.D. rats weighting between 200 g to 250 g were used. The epididymal portion of vas deferens was isolated and was added with various concentrations of serotonin, serotonin antagonists and CHA.

RESULTS: Serotonin elicited dose-dependent (1 × 10

CONCLUSIONS: From the above results, the contraction evoked by CHA on the isolated rat epididymal vas deferens might be mediated by serotonergic receptors through 5-HT

© the Author(s).

Keywords: Cyclohexylamine; Isolated rat epididymal vas deferens; Serotonergic receptors; Serotonin 5-HT2A subtype; primary

Conflict of interest statement

The authors wish to declare no conflicts of interest on this work.

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