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Gromova LV, Ermolenko EI, Sepp AL, et al. Gut Digestive Function and Microbiome after Correction of Experimental Dysbiosis in Rats by Indigenous Bifidobacteria. Microorganisms. 2021;9(3)doi: 10.3390/microorganisms9030522.
Gromova, L. V., Ermolenko, E. I., Sepp, A. L., Dmitrieva, Y. V., Alekseeva, A. S., Lavrenova, N. S., Kotyleva, M. P., Kramskaya, T. A., Karaseva, A. B., Suvorov, A. N., & Gruzdkov, A. A. (2021). Gut Digestive Function and Microbiome after Correction of Experimental Dysbiosis in Rats by Indigenous Bifidobacteria. Microorganisms, 9(3), . https://doi.org/10.3390/microorganisms9030522
Gromova, Lyudmila V, et al. "Gut Digestive Function and Microbiome after Correction of Experimental Dysbiosis in Rats by Indigenous Bifidobacteria." Microorganisms vol. 9,3 (2021). doi: https://doi.org/10.3390/microorganisms9030522
Gromova LV, Ermolenko EI, Sepp AL, Dmitrieva YV, Alekseeva AS, Lavrenova NS, Kotyleva MP, Kramskaya TA, Karaseva AB, Suvorov AN, Gruzdkov AA. Gut Digestive Function and Microbiome after Correction of Experimental Dysbiosis in Rats by Indigenous Bifidobacteria. Microorganisms. 2021 Mar 04;9(3). doi: 10.3390/microorganisms9030522. PMID: 33806341; PMCID: PMC8001560.
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Microorganisms. 2021 Mar 04;9(3). doi: 10.3390/microorganisms9030522.

Gut Digestive Function and Microbiome after Correction of Experimental Dysbiosis in Rats by Indigenous Bifidobacteria.

Microorganisms

Lyudmila V Gromova, Elena I Ermolenko, Anastasiya L Sepp, Yulia V Dmitrieva, Anna S Alekseeva, Nadezhda S Lavrenova, Mariya P Kotyleva, Tatyana A Kramskaya, Alena B Karaseva, Alexandr N Suvorov, Andrey A Gruzdkov

Affiliations

  1. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 Saint-Petersburg, Russia.
  2. Department of Molecular Microbiology, Institute of Experimental Medicine, 197376 Saint-Petersburg, Russia.
  3. Department of Medical Microbiology, North-Western State Medical University Named after I.I. Mechnikov, Ministry of Health of the Russian Federation, 195067 Saint-Petersburg, Russia.
  4. Department of Fundamental Problems of Medicine and Medical Technologies, Saint-Petersburg State University, 199034 Saint-Petersburg, Russia.

PMID: 33806341 PMCID: PMC8001560 DOI: 10.3390/microorganisms9030522

Abstract

In recent years, great interest has arisen in the use of autoprobiotics (indigenous bacteria isolated from the organism and introduced into the same organism after growing). This study aimed to evaluate the effects of indigenous bifidobacteria on intestinal microbiota and digestive enzymes in a rat model of antibiotic-associated dysbiosis. Our results showed that indigenous bifidobacteria (the Bf group) accelerate the disappearance of dyspeptic symptoms in rats and prevent an increase in chyme mass in the upper intestine compared to the group without autoprobiotics (the C1 group), but significantly increase the mass of chyme in the colon compared to the C1 group and the control group (healthy animals). In the Bf group in the gut microbiota, the content of opportunistic bacteria (

Keywords: autoprobiotics; intestinal digestive enzymes; microbiome

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