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Indian J Nephrol. 2020 Nov-Dec;30(6):359-369. doi: 10.4103/ijn.IJN_193_19. Epub 2020 Nov 30.

Recurrent Glomerulonephritis in the Kidney Allograft.

Indian journal of nephrology

Shane A Bobart, Mariam P Alexander, Andrew Bentall

Affiliations

  1. Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
  2. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

PMID: 33840954 PMCID: PMC8023028 DOI: 10.4103/ijn.IJN_193_19

Abstract

Renal transplantation is the preferred form of renal replacement therapy in patients who develop end-stage kidney disease (ESKD). Among the diverse etiologies of ESKD, glomerulonephritis is the third most common cause, behind hypertensive and diabetic kidney disease. Although efforts to prolong graft survival have improved over time with the advent of novel immunosuppression, recurrent glomerulonephritis remains a major threat to renal allograft survival despite concomitant immunosuppression. As a result, clinical expertise, early diagnosis and intervention will help identify recurrent disease and facilitate prompt treatment, thus minimizing graft loss, resulting in improved outcomes. In this review, we highlight the clinicopathologcal characteristics of certain glomerular diseases that recur in the renal allograft.

Copyright: © 2020 Indian Journal of Nephrology.

Keywords: Focal segmental glomerulosclerosis; IgA nephropathy; glomerulonephritis; kidney allograft; lupus nephritis; membranoproliferative; membranous nephropathy; monoclonal gammopathy

Conflict of interest statement

There are no conflicts of interest.

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