Display options
Cite
Good WW, Zenger B, Bergquist JA, et al. Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds. Comput Cardiol (2010). 2021;47doi: 10.22489/cinc.2020.279.
Good, W. W., Zenger, B., Bergquist, J. A., Rupp, L. C., Gillette, K., Plank, G., & MacLeod, R. S. (2020). Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds. Computing in cardiology, 47. https://doi.org/10.22489/cinc.2020.279
Good, Wilson W, et al. "Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds." Computing in cardiology vol. 47 (2020). doi: https://doi.org/10.22489/cinc.2020.279
Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette K, Plank G, MacLeod RS. Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds. Comput Cardiol (2010). 2020 Sep;47. doi: 10.22489/cinc.2020.279. Epub 2021 Feb 10. PMID: 33937430; PMCID: PMC8082333.
Copy Download .nbib Format: NLM
Share it on

Comput Cardiol (2010). 2020 Sep;47. doi: 10.22489/cinc.2020.279. Epub 2021 Feb 10.

Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds.

Computing in cardiology

Wilson W Good, Brian Zenger, Jake A Bergquist, Lindsay C Rupp, Karli Gillette, Gernot Plank, Rob S MacLeod

Affiliations

  1. Scientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
  2. Department of Biomedical Engineering, University of Utah, SLC, UT, USA.
  3. Nora Eccles Cardiovascular Research and Training Institute, University of Utah, SLC, UT, USA.
  4. School of Medicine, University of Utah, SLC, UT, USA.
  5. Institute of Biophysics, Medical University of Graz, Graz, Austria.

PMID: 33937430 PMCID: PMC8082333 DOI: 10.22489/cinc.2020.279

Abstract

Acute myocardial ischemia compromises the ordered electrical activation of the heart, however, because of sampling limitations, volumetric changes in activation have not been measured. We used a large-animal experimental model and high-resolution volumetric mapping to study the effects of ischemia on conduction speeds (CS) throughout the myocardium. We estimated CS and electrocardiographic changes (ST segments) and evaluated the spatial and temporal correlations between them across 11 controlled episodes. We found that ischemia induces significant conduction slowing, reducing the global median speed by 25 cm/s. Furthermore, there was a high

References

  1. Physiol Meas. 2020 Feb 05;41(1):015002 - PubMed
  2. SoftwareX. 2020 Jan-Jun;11:100454 - PubMed
  3. IEEE Trans Biomed Eng. 2021 Mar 30;PP: - PubMed
  4. Am J Physiol. 1977 Sep;233(3):H329-45 - PubMed
  5. Card Electrophysiol Rev. 2002 Sep;6(3):204-8 - PubMed
  6. Funct Imaging Model Heart. 2019 Jun;11504:37-45 - PubMed
  7. IEEE Trans Biomed Eng. 1998 May;45(5):563-71 - PubMed
  8. Comput Biol Med. 2015 Oct 1;65:229-42 - PubMed
  9. J Electrocardiol. 2016 May-Jun;49(3):323-36 - PubMed

Publication Types

Grant support