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Cleve Clin J Med. 2021 May 03;88(5):267-272. doi: 10.3949/ccjm.88a.21010.

Post-acute sequelae of SARS-CoV-2 infection: Caring for the 'long-haulers'.

Cleveland Clinic journal of medicine

Susan Vehar, Marina Boushra, Prince Ntiamoah, Michelle Biehl

Affiliations

  1. Department of Critical Care Medicine; Department of Pulmonary Medicine; Cleveland Clinic, Cleveland, OH [email protected].
  2. Department of Critical Care Medicine, Cleveland Clinic, Cleveland, OH.
  3. Department of Critical Care Medicine; Department of Pulmonary Medicine; Cleveland Clinic, Cleveland, OH.

PMID: 33941600 DOI: 10.3949/ccjm.88a.21010

Abstract

An estimated 10% of COVID-19 survivors continue to experience symptoms several weeks to months after the appearance of initial symptoms, a condition termed post-acute sequelae of SARS-CoV-2 infection (PASC). These patients, also called "long-haulers," most commonly report protracted symptoms of fatigue, cough, dyspnea, chest tightness, difficulty concentrating, arthralgia, olfactory dysfunction, and headache. While age, comorbid medical conditions, and COVID-19 severity are risk factors, young and previously healthy individuals with mild COVID-19 are also at risk. Recognition of symptoms, evaluation, supportive treatment, and attention to medical comorbidities are the cornerstones of medical management.

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