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Clin Epidemiol Glob Health. 2021 Jul-Sep;11:100770. doi: 10.1016/j.cegh.2021.100770. Epub 2021 May 08.

Hematological profile and biochemical markers of COVID-19 non-survivors: A retrospective analysis.

Clinical epidemiology and global health

Mukesh Bairwa, Rajesh Kumar, Kalpana Beniwal, Deepjyoti Kalita, Yogesh Bahurupi

Affiliations

  1. Department of Internal Medicine, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
  2. Department of Nursing, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
  3. Department of Microbiology, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
  4. Department of Community & Family Medicine, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.

PMID: 33997479 PMCID: PMC8106521 DOI: 10.1016/j.cegh.2021.100770

Abstract

BACKGROUND: Coronavirus disease is primarily transmitted through the respiratory route and bodily contact. The fatality in COVID-19 cases was alarming in the initial days. This study analyzes hematological and biochemical markers of COVID-19 non-survivors

MATERIAL AND METHODS: In this single-center study, records of 249 patients hospitalized with COVID-19 were studied for hematological profile and biochemical markers. Records of patients with laboratory-confirmed COVID-19 disease hospitalized between April 14, 2020, to August 15, 2020, were included in the analysis.

RESULTS: Significantly, the disease mortality was associated with increased procalcitonin (

CONCLUSIONS: The clinicians may consider the hematological and biochemical parameters in the patients with COVID-19 in future decision-making. These indicators might support clinical decisions to identify high fatality cases and poor diagnosis in the initial admission phase. In COVID-19 patients, we recommend close monitoring on procalcitonin, C-reactive protein, neutrophils count, and white blood cell count as a clinical indicator for potential progression to critical illness.

© 2021 The Author(s).

Keywords: Biomarkers; C-Reactive protein; COVID-19; Critical illness; l-lactate dehydrogenase

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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