Display options
Cite
Liu W, Yan Q, Xia C, et al. Recent advances in cell membrane coated metal-organic frameworks (MOFs) for tumor therapy. J Mater Chem B. 2021;9(22):4459-4474doi: 10.1039/d1tb00453k.
Liu, W., Yan, Q., Xia, C., Wang, X., Kumar, A., Wang, Y., Liu, Y., Pan, Y., & Liu, J. (2021). Recent advances in cell membrane coated metal-organic frameworks (MOFs) for tumor therapy. Journal of materials chemistry. B, 9(22), 4459-4474. https://doi.org/10.1039/d1tb00453k
Liu, Weicong, et al. "Recent advances in cell membrane coated metal-organic frameworks (MOFs) for tumor therapy." Journal of materials chemistry. B vol. 9,22 (2021): 4459-4474. doi: https://doi.org/10.1039/d1tb00453k
Liu W, Yan Q, Xia C, Wang X, Kumar A, Wang Y, Liu Y, Pan Y, Liu J. Recent advances in cell membrane coated metal-organic frameworks (MOFs) for tumor therapy. J Mater Chem B. 2021 Jun 02;9(22):4459-4474. doi: 10.1039/d1tb00453k. PMID: 33978055.
Copy Download .nbib Format: NLM
Share it on

J Mater Chem B. 2021 Jun 02;9(22):4459-4474. doi: 10.1039/d1tb00453k.

Recent advances in cell membrane coated metal-organic frameworks (MOFs) for tumor therapy.

Journal of materials chemistry. B

Weicong Liu, Qianwen Yan, Chen Xia, Xiaoxiong Wang, Abhinav Kumar, Yan Wang, Yiwei Liu, Ying Pan, Jianqiang Liu

Affiliations

  1. Department of Pharmacy, The First People's Hospital of Foshan (Affiliated FoShan Hospital of Sun Yat-sen University), Foshan 528000, China. [email protected].
  2. Department of Pathology, The First People's Hospital of Foshan, Foshan 528000, China.
  3. School of Civil and Environmental Engineering, Shenzhen Polytechnic, Shenzhen 518055, China. [email protected].
  4. Department of Chemistry, Faculty of Science, University of Lucknow, Lucknow 226 007, India.
  5. Dongguan Key Laboratory of Drug Design and Formulation Technology, Key Laboratory of Research and Development of New Medical Materials of Guangdong Medical University, School of Pharmacy, Guangdong Medical University, Dongguan 523808, China. [email protected].

PMID: 33978055 DOI: 10.1039/d1tb00453k

Abstract

In improving the tumor-targeting ability of metal-organic frameworks (MOFs) for tumor therapy and avoiding the clearance as well as capture by the immune system, there are still several challenges, which limit the development and bio-applications of MOFs. To overcome these challenges, various targeted modification strategies have been proposed. Amongst all the strategies, a promising cell membrane coating method has been explored and utilized for the syntheses of new cell membrane biomimetic MOFs (CMMs). Through such coating, various source cell membranes (e.g., red blood cell, immune cell, cancer cell, platelet, and fusion cell membranes) can be endowed with excellent properties such as long blood circulation, immune escape, and targeting ability. In the presented perspective, the synthetic method, characterization, and research progress in tumor therapy based on CMMs have been summarized. This is because, like many other technologies, the cell membrane coating technology also has several challenges to overcome. Hence, addressing and overcoming such challenges will promote and extend the bio-applications of MOFs which in the future may become a prospective carrier for cancer nano-medicine. Finally, the prospects and challenges of utilizing CMMs for tumor therapy have been discussed.

Substances

MeSH terms

Publication Types