Display options
Cite
Pirman T, Lenardič A, Nemec Svete A, et al. Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency. Biology (Basel). 2021;10(5)doi: 10.3390/biology10050357.
Pirman, T., Lenardič, A., Nemec Svete, A., & Horvat, S. (2021). Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency. Biology, 10(5), . https://doi.org/10.3390/biology10050357
Pirman, Tatjana, et al. "Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency." Biology vol. 10,5 (2021). doi: https://doi.org/10.3390/biology10050357
Pirman T, Lenardič A, Nemec Svete A, Horvat S. Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency. Biology (Basel). 2021 Apr 22;10(5). doi: 10.3390/biology10050357. PMID: 33922324; PMCID: PMC8147123.
Copy Download .nbib Format: NLM
Share it on

Biology (Basel). 2021 Apr 22;10(5). doi: 10.3390/biology10050357.

Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency.

Biology

Tatjana Pirman, Ajda Lenardič, Alenka Nemec Svete, Simon Horvat

Affiliations

  1. Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Groblje 3, 1230 Domžale, Slovenia.
  2. Small Animal Clinic, Veterinary Faculty, University of Ljubljana, Gerbi?eva 60, 1000 Ljubljana, Slovenia.

PMID: 33922324 PMCID: PMC8147123 DOI: 10.3390/biology10050357

Abstract

The objective of this study was to compare the effects of >Your< Iron Syrup, a novel oral liquid iron-containing food supplement, with the commonly prescribed iron sulphate (Fe-sulphate) in a mouse model of diet-induced iron deficiency. Standard inbred BALB/cOlaHsd mice were fed low-iron diet for 11 weeks to induce significant decrease in blood haemoglobin and haematocrit and were then supplemented by gavage with either >Your< Iron Syrup or Fe-sulphate for two weeks. In >Your< Iron Syrup group, several markers of iron deficiency, such as serum iron concentration, transferrin saturation and ferritin level were significantly improved in both female and male mice. Fe-sulphate induced similar responses, except that it did not significantly increase iron serum in females and serum ferritin in both sexes. Fe-sulphate significantly increased liver-iron content which >Your< Iron Syrup did not. Transcription of

Keywords: >Your< Iron Syrup; Fe-sulphate; mice; nutritional iron deficiency; oral supplementation

References

  1. Cell Metab. 2017 Jun 6;25(6):1216-1230 - PubMed
  2. Eur J Nutr. 2009 Mar;48(2):115-9 - PubMed
  3. Int J Biol Sci. 2008 Feb 18;4(1):58-62 - PubMed
  4. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8780-5 - PubMed
  5. J Clin Invest. 2002 Oct;110(7):1037-44 - PubMed
  6. J Nutr. 2006 Dec;136(12):2993-8 - PubMed
  7. Blood. 2004 Apr 1;103(7):2816-21 - PubMed
  8. Nutr Rev. 2011 Nov;69 Suppl 1:S43-8 - PubMed
  9. Nature. 2014 May 15;509(7500):282-3 - PubMed
  10. Int J Vitam Nutr Res. 2004 Nov;74(6):453-61 - PubMed
  11. Blood. 2019 Jan 3;133(1):18-29 - PubMed
  12. J Nutr. 2004 Dec;134(12):3301-4 - PubMed
  13. Br J Nutr. 2004 Jan;91(1):107-12 - PubMed
  14. Eur J Haematol. 2016 Jan;96(1):19-26 - PubMed
  15. Animal. 2012 Feb;6(2):221-6 - PubMed
  16. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4596-601 - PubMed
  17. Br J Haematol. 1996 Sep;94(3):529-32 - PubMed
  18. Int J Hematol. 2018 Jan;107(1):16-30 - PubMed
  19. J Biol Chem. 2001 Mar 16;276(11):7811-9 - PubMed
  20. Br J Nutr. 2011 Jun;105(11):1652-9 - PubMed
  21. Animals (Basel). 2019 Nov 21;9(12): - PubMed
  22. Exp Gerontol. 2009 Sep;44(9):594-600 - PubMed
  23. Nutrition. 2009 Jan;25(1):20-4 - PubMed
  24. Am J Clin Nutr. 2006 Oct;84(4):822-9 - PubMed
  25. Int J Cardiol. 2020 Jun 15;309:95-99 - PubMed
  26. Pharmaceuticals (Basel). 2018 Nov 22;11(4): - PubMed
  27. Nat Methods. 2010 Jun;7(6):447-9 - PubMed
  28. Biochem Pharmacol. 2000 Jan 15;59(2):115-22 - PubMed
  29. PLoS Genet. 2012;8(5):e1002709 - PubMed
  30. Animals (Basel). 2020 Aug 18;10(8): - PubMed
  31. Animals (Basel). 2017 Nov 24;7(12): - PubMed
  32. Animals (Basel). 2020 Sep 14;10(9): - PubMed
  33. Hematol Oncol Clin North Am. 2016 Apr;30(2):247-308 - PubMed
  34. Animals (Basel). 2018 Dec 20;9(1): - PubMed
  35. Growth Horm IGF Res. 2016 Apr;27:7-17 - PubMed
  36. Nat Methods. 2010 Oct;7(10):825-6 - PubMed
  37. PLoS One. 2015 Feb 20;10(2):e0117383 - PubMed
  38. Nutrients. 2018 Sep 21;10(10): - PubMed
  39. Blood. 1997 Feb 1;89(3):1052-7 - PubMed
  40. Am J Clin Nutr. 2007 Apr;85(4):931-45 - PubMed
  41. Methods. 2001 Dec;25(4):386-401 - PubMed
  42. Biochim Biophys Acta. 2012 Sep;1823(9):1434-43 - PubMed
  43. Medicines (Basel). 2019 Aug 05;6(3): - PubMed
  44. Nucleic Acids Res. 2010 Jan;38(Database issue):D792-9 - PubMed

Publication Types

Grant support