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Ann Med Surg (Lond). 2021 Apr 21;65:102335. doi: 10.1016/j.amsu.2021.102335. eCollection 2021 May.

Mucosal urinary secretion revealing adenocarcinoma of urachus.

Annals of medicine and surgery (2012)

Issam Jandou, Adnan Ettanji, Ettaouil Mohammed, Amine Moataz, Dakir Mohammed, Adil Debbagh, Rachid Aboutaieb

Affiliations

  1. University Hospital Center Ibn Rochd Casablanca, Morocco.
  2. Faculté de Médicine et de Pharmacie Casablanca, Morocco.
  3. Laboratoire de Santé Sexuelle, Faculté de Médecine et de Pharmacie, Université Hassan II, Casablanca, Morocco.

PMID: 33996065 PMCID: PMC8093895 DOI: 10.1016/j.amsu.2021.102335

Abstract

INTRODUCTION: Urachus adenocarcinoma is an extremely rare malignant tumor characterized by its insidious evolution responsible for the delay in diagnosis. Several scientific works have tried to study the indication of adjuvant treatment, therefore the prognosis is still poor.

PRESENTATION OF CASE: We report the case of a 50-year-old patient with no pathological history who consulted for an episode of intermittent urinary mucosal secretion aggravated by the appearance of macroscopic hematuria. Without other associated clinical signs. Imaging examinations revealed a mass at the expense of the upper wall of the bladder. The cystoscopy allowed us to visualize the mass and the biopsy. Histological study revealed an adenocarcinoma of urachus. The patient underwent surgical exeresis and adjuvant chemotherapy. The evolution was marked by a deterioration of the general condition despite adequate management.

DISCUSSION: Due to its topography, urachus cancer usually manifests as a bladder tumor, exceptionally as much as an anterior umbilical or extraperitoneal tumor. Few studies have been done on this neoplasm; however surgery still has a primary place in therapeutic management.

CONCLUSION: The scarcity of cases of urachus cancer makes the publications scarce and the lack of multicenter clinical and randomized trials explains the disagreement about adjuvant treatments.

© 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.

Keywords: Bladder cancer; Hematuria; Urachal adenocarcinoma; Urinary mucosal secretion

Conflict of interest statement

All authors disclose any conflicts of interest.

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