Display options
Share it on

Hum Fertil (Camb). 2021 May 25;1-10. doi: 10.1080/14647273.2021.1922764. Epub 2021 May 25.

Genetic and .

Human fertility (Cambridge, England)

João Matheus Bremm, Marcus Michels, Bruna Duarte Rengel, Flavia Gobetti Gomes, Lucas Rosa Fraga, Maria Teresa Vieira Sanseverino

Affiliations

  1. Departament of Genetics, Biosciences Institute, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
  2. Departament of Morphological Sciences, Institute of Health Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
  3. Laboratory of Genomic Medicine, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  4. Graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
  5. School of Medicine, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, Brazil.
  6. Medical Genetics Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

PMID: 34030553 DOI: 10.1080/14647273.2021.1922764

Abstract

Recurrent pregnancy loss (RPL) is one of the most common reproductive failures affecting 1-5% of couples. Smad3 is an effector of signalling of the Transforming Growth Factors-β superfamily (TGF-β), regulating the transcription of several target genes of these cytokines. The objective of this study was to evaluate the influence of a variant on

Keywords: Gene Expression Omnibus; Pregnancy; TGF-β; hormone response; recurrent miscarriage; rs17293443

Publication Types