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Chen YW, Wengler K, He X, et al. Individual Differences in Cerebral Perfusion as a Function of Age and Loneliness. Exp Aging Res. 2021;1-23doi: 10.1080/0361073X.2021.1929748.
Chen, Y. W., Wengler, K., He, X., & Canli, T. (2021). Individual Differences in Cerebral Perfusion as a Function of Age and Loneliness. Experimental aging research, 1-23. https://doi.org/10.1080/0361073X.2021.1929748
Chen, Yen-Wen, et al. "Individual Differences in Cerebral Perfusion as a Function of Age and Loneliness." Experimental aging research vol. (2021): 1-23. doi: https://doi.org/10.1080/0361073X.2021.1929748
Chen YW, Wengler K, He X, Canli T. Individual Differences in Cerebral Perfusion as a Function of Age and Loneliness. Exp Aging Res. 2021 May 26;1-23. doi: 10.1080/0361073X.2021.1929748. Epub 2021 May 26. PMID: 34036895; PMCID: PMC8617054.
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Exp Aging Res. 2021 May 26;1-23. doi: 10.1080/0361073X.2021.1929748. Epub 2021 May 26.

Individual Differences in Cerebral Perfusion as a Function of Age and Loneliness.

Experimental aging research

Yen-Wen Chen, Kenneth Wengler, Xiang He, Turhan Canli

Affiliations

  1. Department of Psychology, Stony Brook University, NY, USA.
  2. Department of Biomedical Engineering, Stony Brook University, NY, USA.
  3. Present Address: Now at New York State Psychiatric Institute, Columbia University, NY, USA.
  4. Department of Radiology, Stony Brook University, NY, USA.
  5. Department of Psychiatry, Stony Brook University, NY, USA.

PMID: 34036895 PMCID: PMC8617054 DOI: 10.1080/0361073X.2021.1929748

Abstract

Loneliness is defined as the subjective feeling that one's social needs are not satisfied by both quantity and quality of one's social relationships. Loneliness has been linked to a broad range of adverse physical and mental health consequences. There is an interest in identifying the neural and molecular processes by which loneliness adversely affects health. Prior imaging studies reported divergent networks involved in cognitive, emotional, and social processes associated with loneliness. Although loneliness is common among both younger and older adults, it is experienced differently across the lifespan and has different antecedents and consequences. The current study measured regional cerebral blood flow (CBF) using pulsed arterial spin labeling imaging. Forty-five older (

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