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Pharmaceutics. 2021 May 20;13(5). doi: 10.3390/pharmaceutics13050764.

DNA-Binding and Cytotoxicity of Copper(I) Complexes Containing Functionalized Dipyridylphenazine Ligands.

Pharmaceutics

Sammar Alsaedi, Bandar A Babgi, Magda H Abdellattif, Muhammad N Arshad, Abdul-Hamid M Emwas, Mariusz Jaremko, Mark G Humphrey, Abdullah M Asiri, Mostafa A Hussien

Affiliations

  1. Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
  2. Chemistry Department, Deanship of Scientific Research, College of Sciences, Taif University, Al-Haweiah, P.O. Box 11099, Taif 21944, Saudi Arabia.
  3. Center of Excellence for Advanced Materials Research (CEAMR), King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
  4. Core Labs, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.
  5. Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
  6. Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia.
  7. Department of Chemistry, Faculty of Science, Port Said University, Port Said 42521, Egypt.

PMID: 34065613 PMCID: PMC8161420 DOI: 10.3390/pharmaceutics13050764

Abstract

A set of copper(I) coordination compounds with general formula [CuBr(PPh

Keywords: Copper(I); DNA-binding; anticancer properties; dipyridophenazine; molecular docking

References

  1. BMC Cancer. 2006 Nov 15;6:267 - PubMed
  2. Anticancer Agents Med Chem. 2009 Feb;9(2):185-211 - PubMed
  3. Acta Crystallogr C Struct Chem. 2015 Jan;71(Pt 1):9-18 - PubMed
  4. J Cell Mol Med. 2012 Jan;16(1):142-51 - PubMed
  5. Metallomics. 2012 Feb;4(2):127-38 - PubMed
  6. J Fluoresc. 2017 Nov;27(6):2119-2130 - PubMed
  7. J Inorg Biochem. 2006 Mar;100(3):316-30 - PubMed
  8. J Inorg Biochem. 2011 Aug;105(8):1102-8 - PubMed
  9. J Nat Prod. 1991 Nov-Dec;54(6):1522-30 - PubMed
  10. J Natl Cancer Inst. 1990 Jul 4;82(13):1107-12 - PubMed
  11. Dalton Trans. 2016 Feb 7;45(5):2250-60 - PubMed
  12. Molecules. 2020 Oct 14;25(20): - PubMed
  13. Nat Commun. 2018 Oct 18;9(1):4335 - PubMed
  14. Dalton Trans. 2018 Feb 6;47(6):1981-1992 - PubMed
  15. Chem Rev. 1999 Sep 8;99(9):2451-66 - PubMed
  16. Chem Rev. 2014 Jan 8;114(1):815-62 - PubMed
  17. Drug Resist Updat. 2008 Feb-Apr;11(1-2):1-16 - PubMed
  18. Curr Med Chem. 2006;13(11):1337-57 - PubMed
  19. J Med Chem. 2008 Feb 28;51(4):798-808 - PubMed
  20. Invest New Drugs. 2011 Dec;29(6):1213-23 - PubMed
  21. Acta Crystallogr C Struct Chem. 2015 Jan;71(Pt 1):3-8 - PubMed
  22. Dalton Trans. 2016 Mar 28;45(12):5052-63 - PubMed
  23. Inorg Chem. 2017 Apr 3;56(7):3781-3793 - PubMed
  24. Dalton Trans. 2013 Jul 21;42(27):9826-30 - PubMed
  25. Cancer Treat Rev. 2007 Feb;33(1):9-23 - PubMed

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