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Zimmerman J, Blackard JT. Human pegivirus type 1 infection in Asia-A review of the literature. Rev Med Virol. 2021;e2257doi: 10.1002/rmv.2257.
Zimmerman, J., & Blackard, J. T. (2021). Human pegivirus type 1 infection in Asia-A review of the literature. Reviews in medical virology, e2257. https://doi.org/10.1002/rmv.2257
Zimmerman, Joseph, and Blackard, Jason T. "Human pegivirus type 1 infection in Asia-A review of the literature." Reviews in medical virology vol. (2021): e2257. doi: https://doi.org/10.1002/rmv.2257
Zimmerman J, Blackard JT. Human pegivirus type 1 infection in Asia-A review of the literature. Rev Med Virol. 2021 May 26;e2257. doi: 10.1002/rmv.2257. Epub 2021 May 26. PMID: 34038600.
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Rev Med Virol. 2021 May 26;e2257. doi: 10.1002/rmv.2257. Epub 2021 May 26.

Human pegivirus type 1 infection in Asia-A review of the literature.

Reviews in medical virology

Joseph Zimmerman, Jason T Blackard

Affiliations

  1. Division of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

PMID: 34038600 DOI: 10.1002/rmv.2257

Abstract

The human pegivirus type 1 (HPgV-1)-as known as hepatitis G virus and GB virus C-is a common single-stranded RNA flavivirus. Because few studies have demonstrated an association between HPgV-1 infection and disease, screening for HPgV-1 is not performed routinely. Nonetheless, a beneficial impact of HPgV-1 infection on HIV disease progression has been reported in multiple studies. Given the burden of HIV in Asia and the complex interactions between viral co-infections and the host, we provide a comprehensive overview of the existing data from Asia on HPgV-1 infection, including the prevalence and circulating genotypes in all Asian countries with data reported. This review highlights the research conducted thus far and emphasizes the need for additional studies on HPgV-1 across the Asian continent.

© 2021 John Wiley & Sons Ltd.

Keywords: Asia; GB virus C; GBV-C; HIV; HPgV-1; genotype; hepatitis G virus; pegivirus

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