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Naber A, Reiß M, Nahm W. Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error. Front Physiol. 2021;12:588120doi: 10.3389/fphys.2021.588120.
Naber, A., Reiß, M., & Nahm, W. (2021). Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error. Frontiers in physiology, 12588120. https://doi.org/10.3389/fphys.2021.588120
Naber, Ady, et al. "Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error." Frontiers in physiology vol. 12 (2021): 588120. doi: https://doi.org/10.3389/fphys.2021.588120
Naber A, Reiß M, Nahm W. Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error. Front Physiol. 2021 May 28;12:588120. doi: 10.3389/fphys.2021.588120. eCollection 2021. PMID: 34122123; PMCID: PMC8194354.
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Front Physiol. 2021 May 28;12:588120. doi: 10.3389/fphys.2021.588120. eCollection 2021.

Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error.

Frontiers in physiology

Ady Naber, Michael Reiß, Werner Nahm

Affiliations

  1. Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany.

PMID: 34122123 PMCID: PMC8194354 DOI: 10.3389/fphys.2021.588120

Abstract

The vascular function of a vessel can be qualitatively and intraoperatively checked by recording the blood dynamics inside the vessel via fluorescence angiography (FA). Although FA is the state of the art in proving the existence of blood flow during interventions such as bypass surgery, it still lacks a quantitative blood flow measurement that could decrease the recurrence rate and postsurgical mortality. Previous approaches show that the measured flow has a significant deviation compared to the gold standard reference (ultrasonic flow meter). In order to systematically address the possible sources of error, we investigated the error in transit time measurement of an indicator. Obtaining

Copyright © 2021 Naber, Reiß and Nahm.

Keywords: blood flow velocity; fluorescence angiography; indicator dilution curve; mathematical fits; sub-frame rate accuracy; transit time

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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