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Sprowls SA, Saralkar P, Arsiwala T, et al. A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions. Pharmaceutics. 2021;13(5)doi: 10.3390/pharmaceutics13050756.
Sprowls, S. A., Saralkar, P., Arsiwala, T., Adkins, C. E., Blethen, K. E., Pizzuti, V. J., Shah, N., Fladeland, R., & Lockman, P. R. (2021). A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions. Pharmaceutics, 13(5), . https://doi.org/10.3390/pharmaceutics13050756
Sprowls, Samuel A, et al. "A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions." Pharmaceutics vol. 13,5 (2021). doi: https://doi.org/10.3390/pharmaceutics13050756
Sprowls SA, Saralkar P, Arsiwala T, Adkins CE, Blethen KE, Pizzuti VJ, Shah N, Fladeland R, Lockman PR. A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions. Pharmaceutics. 2021 May 19;13(5). doi: 10.3390/pharmaceutics13050756. PMID: 34069733; PMCID: PMC8160855.
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Pharmaceutics. 2021 May 19;13(5). doi: 10.3390/pharmaceutics13050756.

A Review of Mathematics Determining Solute Uptake at the Blood-Brain Barrier in Normal and Pathological Conditions.

Pharmaceutics

Samuel A Sprowls, Pushkar Saralkar, Tasneem Arsiwala, Christopher E Adkins, Kathryn E Blethen, Vincenzo J Pizzuti, Neal Shah, Ross Fladeland, Paul R Lockman

Affiliations

  1. Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA.
  2. Health Sciences Center, West Virginia University, Morgantown, WV 26506, USA.
  3. School of Pharmacy, South University, Savannah, GA 31406, USA.
  4. Department of Dermatology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.

PMID: 34069733 PMCID: PMC8160855 DOI: 10.3390/pharmaceutics13050756

Abstract

The blood-brain barrier (BBB) limits movement of solutes from the lumen of the brain microvascular capillary system into the parenchyma. The unidirectional transfer constant,

Keywords: blood–brain barrier; brain; magnetic-resonance imaging; pharmacokinetics; preclinical models

References

  1. J Control Release. 2014 Oct 28;192:1-9 - PubMed
  2. J Neurosci Methods. 2013 Sep 30;219(1):188-95 - PubMed
  3. J Cereb Blood Flow Metab. 1985 Jun;5(2):300-11 - PubMed
  4. J Cereb Blood Flow Metab. 1983 Mar;3(1):1-7 - PubMed
  5. Trends Cancer. 2019 Aug;5(8):495-505 - PubMed
  6. Front Pharmacol. 2013 Nov 04;4:136 - PubMed
  7. J Neurochem. 2001 Feb;76(4):1032-41 - PubMed
  8. AJNR Am J Neuroradiol. 2004 May;25(5):746-55 - PubMed
  9. J Magn Reson Imaging. 2012 Aug;36(2):355-63 - PubMed
  10. J Clin Oncol. 2007 Jun 1;25(16):2306-12 - PubMed
  11. Neuroimage. 2003 Nov;20(3):1775-82 - PubMed
  12. Am J Physiol. 1978 Sep;235(3):H299-307 - PubMed
  13. Neurobiol Dis. 2010 Jan;37(1):13-25 - PubMed
  14. Am J Physiol. 1971 Dec;221(6):1629-39 - PubMed
  15. J Neurosci. 2012 Jul 11;32(28):9588-600 - PubMed
  16. Pharm Res. 1995 Dec;12(12):1838-44 - PubMed
  17. J Neurochem. 2010 Dec;115(6):1495-507 - PubMed
  18. Front Neurosci. 2017 Feb 23;11:86 - PubMed
  19. Ther Deliv. 2015;6(8):961-71 - PubMed
  20. Circ Res. 1985 Aug;57(2):213-22 - PubMed
  21. Am J Physiol. 1975 Oct;229(4):877-84 - PubMed
  22. Pharm Res. 2003 Apr;20(4):618-23 - PubMed
  23. Cell. 2015 Nov 19;163(5):1064-1078 - PubMed
  24. Expert Opin Drug Deliv. 2016 Jul;13(7):963-75 - PubMed
  25. AAPS J. 2017 Sep;19(5):1294-1303 - PubMed
  26. BMC Cancer. 2018 Dec 7;18(1):1225 - PubMed
  27. Curr Pharm Des. 2011;17(26):2793-802 - PubMed
  28. J Cereb Blood Flow Metab. 1987 Dec;7(6):687-701 - PubMed
  29. J Pharm Sci. 2011 Sep;100(9):3547-59 - PubMed
  30. J Cereb Blood Flow Metab. 1983 Mar;3(1):8-32 - PubMed
  31. Curr Med Imaging Rev. 2009 May 1;3(2):91-107 - PubMed
  32. Drug Metab Dispos. 2006 Feb;34(2):318-23 - PubMed
  33. Am J Physiol. 1976 Feb;230(2):543-52 - PubMed
  34. Br J Pharmacol. 2009 Oct;158(3):693-705 - PubMed
  35. Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):3-26 - PubMed
  36. NeuroRx. 2005 Jan;2(1):86-98 - PubMed
  37. Cardiovasc Diagn Ther. 2014 Apr;4(2):147-64 - PubMed
  38. Adv Drug Deliv Rev. 2004 Oct 14;56(12):1793-809 - PubMed
  39. Cold Spring Harb Perspect Biol. 2015 Jan 05;7(1):a020412 - PubMed
  40. J Neurochem. 2003 Aug;86(3):627-34 - PubMed
  41. Pharm Res. 2009 Nov;26(11):2486-94 - PubMed
  42. Methods Mol Med. 2003;89:193-208 - PubMed
  43. J Magn Reson Imaging. 1997 Jan-Feb;7(1):91-101 - PubMed
  44. Drug Metab Dispos. 2006 Sep;34(9):1624-31 - PubMed
  45. Clin Cancer Res. 2010 Dec 1;16(23):5664-78 - PubMed
  46. J Pharmacol Exp Ther. 2008 Jan;324(1):244-50 - PubMed
  47. J Pharmacol Exp Ther. 2005 Aug;314(2):636-42 - PubMed
  48. Expert Rev Neurother. 2006 Aug;6(8):1199-209 - PubMed
  49. Trends Neurosci. 2013 Oct;36(10):587-97 - PubMed
  50. Clin Exp Pharmacol Physiol. 1990 Dec;17(12):829-40 - PubMed
  51. Ann N Y Acad Sci. 1986;481:186-201 - PubMed
  52. AJNR Am J Neuroradiol. 2008 Apr;29(4):694-700 - PubMed
  53. ISRN Neurosci. 2013 Feb 20;2013:905279 - PubMed
  54. Neurology. 2017 Jan 31;88(5):433-440 - PubMed
  55. Methods Mol Med. 2003;89:209-18 - PubMed
  56. Mol Pharm. 2018 Dec 3;15(12):5493-5500 - PubMed
  57. Stroke. 2014 Jul;45(7):2030-5 - PubMed
  58. J Clin Invest. 1989 Oct;84(4):1155-9 - PubMed
  59. Front Neuroeng. 2013 Aug 30;6:7 - PubMed
  60. Adv Pharmacol. 2014;71:147-63 - PubMed
  61. J Pharm Sci. 2011 Sep;100(9):3731-50 - PubMed
  62. J Angiogenes Res. 2009 Sep 21;1:5 - PubMed
  63. Stroke Vasc Neurol. 2018 Dec 5;4(2):78-82 - PubMed
  64. Acta Physiol Scand. 1963 Aug;58:292-305 - PubMed
  65. Pharm Res. 2008 Aug;25(8):1737-50 - PubMed
  66. Fluids Barriers CNS. 2019 May 16;16(1):12 - PubMed
  67. Am J Physiol. 1984 Sep;247(3 Pt 2):H484-93 - PubMed
  68. Handb Exp Pharmacol. 2020 Dec 01;: - PubMed
  69. J Neurooncol. 1984;2(3):195-204 - PubMed
  70. Methods Mol Med. 2003;89:177-90 - PubMed
  71. J Magn Reson Imaging. 1999 Sep;10(3):223-32 - PubMed

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