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Gómez Herrero H, Galbete A, Álvarez Galván B, et al. Lesiones residuales en radiografía simple de tórax tras neumonía por SARS-CoV-2: identificación de factores de riesgo. Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors. Med Clin (Barc). 2021;doi: 10.1016/j.medcli.2021.04.001.
Gómez Herrero, H., Galbete, A., Álvarez Galván, B., Caballero García, P., & Vicaría Fernández, I. (2021). Lesiones residuales en radiografía simple de tórax tras neumonía por SARS-CoV-2: identificación de factores de riesgo. Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors. Medicina clinica, . https://doi.org/10.1016/j.medcli.2021.04.001
Gómez Herrero, Helena, et al. "Lesiones residuales en radiografía simple de tórax tras neumonía por SARS-CoV-2: identificación de factores de riesgo." Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors. Medicina clinica vol. (2021). doi: https://doi.org/10.1016/j.medcli.2021.04.001
Gómez Herrero H, Galbete A, Álvarez Galván B, Caballero García P, Vicaría Fernández I. Lesiones residuales en radiografía simple de tórax tras neumonía por SARS-CoV-2: identificación de factores de riesgo. Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors. Med Clin (Barc). 2021 May 06; doi: 10.1016/j.medcli.2021.04.001. Epub 2021 May 06. Spanish. PMID: 34059358; PMCID: PMC8101868.
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Med Clin (Barc). 2021 May 06; doi: 10.1016/j.medcli.2021.04.001. Epub 2021 May 06.

Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors.

Medicina clinica

[Article in Spanish]
Helena Gómez Herrero, Arkaitz Galbete, Begoña Álvarez Galván, Pilar Caballero García, Iván Vicaría Fernández

Affiliations

  1. Servicio de Radiología, Complejo Hospitalario de Navarra, Pamplona, España. Electronic address: [email protected].
  2. Navarrabiomed-Complejo Hospitalario de Navarra-Universidad Pública de Navarra, IdiSNA, REDISSEC, Pamplona, España.
  3. Servicio de Radiología, Complejo Hospitalario de Navarra, Pamplona, España.

PMID: 34059358 PMCID: PMC8101868 DOI: 10.1016/j.medcli.2021.04.001

Abstract

INTRODUCTION: COVID-19 pneumonia is the most frequent clinical manifestation of this disease, and its long-term sequelae and possible progression to pulmonary fibrosis are still unknown. The aim of this study is a mid-term review of the sequelae on plain chest radiography (CXR) in patients with a previous diagnosis of COVID-19 pneumonia.

PATIENTS AND METHODS: Retrospective review of patients with a diagnosis of COVID-19 pneumonia, assessing the persistence of residual lesions in the control CXR and analysing their possible relationship with epidemiological factors, risk factors, treatments received and initial radiological patterns.

RESULTS: A total of 143 patients (52 women and 91 men) were analysed. Mean age was 64 years. Radiological complete resolution (CR) was observed in 104 (73%) and partial resolution (PR) in 39 (27%). Of the risk factors only age was significantly related to persistence of residual lesions (OR 1.06 CI 95% (1.02,1.10). In relation to treatments, significant differences were found with tocilizumab and glucocorticoids, where treated patients had a higher risk of residual lesions (OR 2.44 (1.03,5.80) and 3.05(1.43,6.51) respectively. In the analysis of radiological patterns, significant differences were observed in patients with peripheral condensations in the acute course and a pattern of early radiological worsening. A clinical-radiological dissociation was evident: 83% of patients with residual lesions had no respiratory symptoms.

DISCUSSION: COVID19 pneumonias may have a slower radiological resolution in older patients with certain initial radiological patterns, but the development of pulmonary fibrosis in these patients is still questionable.

Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

Keywords: Chest X-ray; Coronavirus disease; Enfermedad por coronavirus; Fibrosis pulmonar; Lung fibrosis; Radiografía de tórax

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