Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.

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J Immunol. 2021 Jun 11; doi: 10.4049/jimmunol.2001208. Epub 2021 Jun 11.

Journal of immunology (Baltimore, Md. : 1950)

Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Laboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Department of Pediatrics, Harvard Medical School, Boston, MA.
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY.
Department of Biology and Biochemistry, University of Houston, Houston, TX.
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA; and.
Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark; [email protected].

Complement receptor 3 (CR3, also known as Mac-1, integrin α