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Annu Rev Biochem. 2021 Jun 20;90:57-76. doi: 10.1146/annurev-biochem-062320-062929.

From Bioorganic Models to Cells.

Annual review of biochemistry

Stephen J Benkovic

Affiliations

  1. Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA; email: [email protected].

PMID: 34153218 DOI: 10.1146/annurev-biochem-062320-062929

Abstract

I endeavor to share how various choices-some deliberate, some unconscious-and the unmistakable influence of many others shaped my scientific pursuits. I am fascinated by how two long-term, major streams of my research, DNA replication and purine biosynthesis, have merged with unexpected interconnections. If I have imparted to many of the talented individuals who have passed through my lab a degree of my passion for uncloaking the mysteries hidden in scientific research and an understanding of the honesty and rigor it demands and its impact on the world community, then my mentorship has been successful.

Keywords: DNA replication; autobiography; enzymatic catalysis; purine biosynthesis

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