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Salama M, Isachenko E, Rahimi G, et al. Emergency Fertility Preservation in a Young Woman With Non-Hodgkin Lymphoma. Oncology (Williston Park). 2021;35(6):332-334doi: 10.46883/ONC.2021.3506.0332.
Salama, M., Isachenko, E., Rahimi, G., Mallmann, P., & Isachenko, V. (2021). Emergency Fertility Preservation in a Young Woman With Non-Hodgkin Lymphoma. Oncology (Williston Park, N.Y.), 35(6), 332-334. https://doi.org/10.46883/ONC.2021.3506.0332
Salama, Mahmoud, et al. "Emergency Fertility Preservation in a Young Woman With Non-Hodgkin Lymphoma." Oncology (Williston Park, N.Y.) vol. 35,6 (2021): 332-334. doi: https://doi.org/10.46883/ONC.2021.3506.0332
Salama M, Isachenko E, Rahimi G, Mallmann P, Isachenko V. Emergency Fertility Preservation in a Young Woman With Non-Hodgkin Lymphoma. Oncology (Williston Park). 2021 Jun 19;35(6):332-334. doi: 10.46883/ONC.2021.3506.0332. PMID: 34147055.
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Oncology (Williston Park). 2021 Jun 19;35(6):332-334. doi: 10.46883/ONC.2021.3506.0332.

Emergency Fertility Preservation in a Young Woman With Non-Hodgkin Lymphoma.

Oncology (Williston Park, N.Y.)

Mahmoud Salama, Evgenia Isachenko, Gohar Rahimi, Peter Mallmann, Vladimir Isachenko

Affiliations

  1. Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, East Lansing, MI.
  2. Department of Obstetrics & Gynecology, University of Cologne, Cologne, Germany.

PMID: 34147055 DOI: 10.46883/ONC.2021.3506.0332

Abstract

A nulliparous woman, age 25 years, had received a diagnosis of non-Hodgkin lymphoma (NHL) and now presented with stage IIA diffuse large B-cell lymphoma (DLBCL). According to her hematological oncologist's treatment plan, chemotherapy had to start immediately (within 1 week), with the patient receiving 6 courses of the standard R-CHOEP21 regimen (rituximab 375 mg/m², cyclophosphamide 750 mg/m², hydroxydaunorubicin 50 mg/m², vincristine 1.4 mg/m², etoposide 100 mg/m², prednisone 40 mg/m²). Due to potential risks of chemotherapy-induced gonadotoxicity and subsequent iatrogenic premature ovarian failure (POF) and fertility loss, the patient was referred to the reproductive medicine department for fertility preservation counseling and further management.

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