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Flores RL, Rossi R, Castiblanco A, et al. Solid bifocal pseudopapillary neoplasm of the pancreas: A case report. Int J Surg Case Rep. 2021;84:106131doi: 10.1016/j.ijscr.2021.106131.
Flores, R. L., Rossi, R., Castiblanco, A., Gallardo, A., & Schiappacasse, G. (2021). Solid bifocal pseudopapillary neoplasm of the pancreas: A case report. International journal of surgery case reports, 84106131. https://doi.org/10.1016/j.ijscr.2021.106131
Flores, Rubén Lima, et al. "Solid bifocal pseudopapillary neoplasm of the pancreas: A case report." International journal of surgery case reports vol. 84 (2021): 106131. doi: https://doi.org/10.1016/j.ijscr.2021.106131
Flores RL, Rossi R, Castiblanco A, Gallardo A, Schiappacasse G. Solid bifocal pseudopapillary neoplasm of the pancreas: A case report. Int J Surg Case Rep. 2021 Jul;84:106131. doi: 10.1016/j.ijscr.2021.106131. Epub 2021 Jun 25. PMID: 34182434; PMCID: PMC8253944.
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Int J Surg Case Rep. 2021 Jul;84:106131. doi: 10.1016/j.ijscr.2021.106131. Epub 2021 Jun 25.

Solid bifocal pseudopapillary neoplasm of the pancreas: A case report.

International journal of surgery case reports

Rubén Lima Flores, Ricardo Rossi, Adriana Castiblanco, Alejandra Gallardo, Giancarlo Schiappacasse

Affiliations

  1. Department of Digestive and Soft Tissue Oncologic Surgery, Instituto Nacional del Cáncer, Santiago, Chile. Electronic address: [email protected].
  2. Department of Hepato-bilio-pancreatic Surgery, Faculty of Medicine, Clínica Alemana de Santiago, Santiago, Chile.
  3. Pathology Department, Faculty of Medicine, Clínica Alemana de Santiago, Santiago, Chile.
  4. Imagenologic Department, Faculty of Medicine, Clínica Alemana de Santiago, Santiago, Chile.

PMID: 34182434 PMCID: PMC8253944 DOI: 10.1016/j.ijscr.2021.106131

Abstract

INTRODUCTION: This neoplasm of the pancreas is an uncommon entity, with a frequency of 0.3-2.7% of all pancreatic tumors and even more so the finding of a synchronous lesion of the same histological lineage. For this reason, we report the atypical presentation of a SPNPs through a clinical case, review of the literature and a classification proposal, from the quantitative point of view.

CASE PRESENTATION: 21-year-old patient, with incidental finding of two pancreatic tumors. Surgery included a pyloric preserving pancreatoduodenectomy with pancreatojejunostomy, distal pancreatectomy and central pancreas was preserved. The patient presents low output pancreatic fistula and nosocomial infection, treated with antibiotic therapy, being discharged 29 days after the intervention. Pathological and immunohistochemical analysis consistent with two SPNP.

DISCUSSION: Its diagnosis is confirmed with the histological study and two synchronic SPNP are a rare entity and for this, or multiple lesions, an attempt should be made of a conservative resection of the parenchyma to minimize pancreatic insufficiency in a frequently young population, and always look for R0 resection, due to its uncertain behavior.

CONCLUSION: Bifocal SPNP is rare and for this it is utility classify this entity -from the quantitative point of view- into unifocal, bifocal and multifocal for future medical research.

Copyright © 2021. Published by Elsevier Ltd.

Keywords: Case report; Franz's tumor; Solid pseudopapillary neoplasia of the pancreas; Solid tumors of the pancreas

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