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Leone M, Cazorla-Vázquez S, Ferrazzi F, et al. IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability. Mol Cancer Res. 2021;19(10):1712-1726doi: 10.1158/1541-7786.MCR-20-0639.
Leone, M., Cazorla-Vázquez, S., Ferrazzi, F., Wiederstein, J. L., Gründl, M., Weinstock, G., Vergarajauregui, S., Eckstein, M., Krüger, M., Gaubatz, S., & Engel, F. B. (2021). IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability. Molecular cancer research : MCR, 19(10), 1712-1726. https://doi.org/10.1158/1541-7786.MCR-20-0639
Leone, Marina, et al. "IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability." Molecular cancer research : MCR vol. 19,10 (2021): 1712-1726. doi: https://doi.org/10.1158/1541-7786.MCR-20-0639
Leone M, Cazorla-Vázquez S, Ferrazzi F, Wiederstein JL, Gründl M, Weinstock G, Vergarajauregui S, Eckstein M, Krüger M, Gaubatz S, Engel FB. IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability. Mol Cancer Res. 2021 Oct;19(10):1712-1726. doi: 10.1158/1541-7786.MCR-20-0639. Epub 2021 Jun 28. PMID: 34183451.
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Mol Cancer Res. 2021 Oct;19(10):1712-1726. doi: 10.1158/1541-7786.MCR-20-0639. Epub 2021 Jun 28.

IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability.

Molecular cancer research : MCR

Marina Leone, Salvador Cazorla-Vázquez, Fulvia Ferrazzi, Janica L Wiederstein, Marco Gründl, Grit Weinstock, Silvia Vergarajauregui, Markus Eckstein, Marcus Krüger, Stefan Gaubatz, Felix B Engel

Affiliations

  1. Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. [email protected] [email protected].
  2. Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  3. Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  4. Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  5. Muscle Research Center Erlangen (MURCE), Erlangen, Germany.
  6. Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  7. Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Wuerzburg, Wuerzburg, Germany.
  8. Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Erlangen, Germany.

PMID: 34183451 DOI: 10.1158/1541-7786.MCR-20-0639

Abstract

Controlling cell proliferation is critical for organism development, tissue homeostasis, disease, and regeneration. IQGAP3 has been shown to be required for proper cell proliferation and migration, and is associated to a number of cancers. Moreover, its expression is inversely correlated with the overall survival rate in the majority of cancers. Here, we show that

©2021 American Association for Cancer Research.

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