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Richardson S, Gitlin J, Kozel Z, et al. In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study. Open Forum Infect Dis. 2021;8(6):ofab233doi: 10.1093/ofid/ofab233.
Richardson, S., Gitlin, J., Kozel, Z., Levy, S., Rahman, H., Hirsch, J. S., McGinn, T., & Diefenbach, M. A. (2021). In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study. Open forum infectious diseases, 8(6), ofab233. https://doi.org/10.1093/ofid/ofab233
Richardson, Safiya, et al. "In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study." Open forum infectious diseases vol. 8,6 (2021): ofab233. doi: https://doi.org/10.1093/ofid/ofab233
Richardson S, Gitlin J, Kozel Z, Levy S, Rahman H, Hirsch JS, McGinn T, Diefenbach MA. In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study. Open Forum Infect Dis. 2021 May 07;8(6):ofab233. doi: 10.1093/ofid/ofab233. eCollection 2021 Jun. PMID: 34183983; PMCID: PMC8135976.
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Open Forum Infect Dis. 2021 May 07;8(6):ofab233. doi: 10.1093/ofid/ofab233. eCollection 2021 Jun.

In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study.

Open forum infectious diseases

Safiya Richardson, Jordan Gitlin, Zachary Kozel, Sera Levy, Husneara Rahman, Jamie S Hirsch, Thomas McGinn, Michael A Diefenbach

Affiliations

  1. Institute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, USA.
  2. Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, New York, USA.
  3. Biostatistics Unit, Feinstein Institutes for Medical Research, Northwell Health, Great Neck, New York, USA.
  4. Department of Information Services, Northwell Health, New Hyde Park, New York, USA.

PMID: 34183983 PMCID: PMC8135976 DOI: 10.1093/ofid/ofab233

Abstract

BACKGROUND: Our objective was to characterize young adult patients hospitalized with coronavirus disease 2019 (COVID-19) and identify predictors of survival at 30 days.

METHODS: This retrospective cohort study took place at 12 acute care hospitals in the New York City area. Patients aged 18-39 hospitalized with confirmed COVID-19 between March 1 and April 27, 2020 were included in the study. Demographic, clinical, and outcome data were extracted from electronic health record reports.

RESULTS: A total of 1013 patients were included in the study (median age, 33 years; interquartile range [IQR], 28-36; 52% female). At the study end point, 940 (92.8%) patients were discharged alive, 18 (1.8%) remained hospitalized, 5 (0.5%) were transferred to another acute care facility, and 50 (4.9%) died. The most common comorbidities in hospitalized young adult patients were obesity (51.2%), diabetes mellitus (14.8%), and hypertension (13%). Multivariable analysis revealed that obesity (adjusted hazard ratio [aHR], 2.71; 95% confidence interval [CI], 1.28-5.73;

CONCLUSIONS: Obesity was identified as the strongest negative predictor of 30-day in-hospital survival in young adults with COVID-19.

© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

Keywords: coronavirus disease 2019 (COVID-19); mortality; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); young adults

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