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Curr Health Sci J. 2021 Jan-Mar;47(1):101-106. doi: 10.12865/CHSJ.47.01.16. Epub 2021 Mar 31.

Doppler Uterine Artery Ultrasound in the Second Trimester of Pregnancy to Predict Adverse Pregnancy Outcomes.

Current health sciences journal

Manuela Stoenescu, Mircea-Sebastian Serbanescu, Anda Lorena Dijmarescu, Maria Magdalena Manolea, Liliana Novac, Adriana Tudor, Carmen Tabacu

Affiliations

  1. PhD Student, University of Medicine and Pharmacy of Craiova, Romania.
  2. Department of Medical Informatics, University of Medicine and Pharmacology of Craiova, Romania.
  3. Department of Obstetrics and Gynecology, University of Medicine and Pharmacology of Craiova, Romania.

PMID: 34211755 PMCID: PMC8200604 DOI: 10.12865/CHSJ.47.01.16

Abstract

PURPOSE: To determine in uterine artery (UtA) the mean pulsatility index (PI), systolic/diastolic (S/D) ratio and the presence/absence of notch in the second trimester of pregnancy, with normal or abnormal pregnancy outcome.

MATERIAL AND METHODS: We performed an analysis of 135 cases with high risk pregnancy in Obstetrics and Gynecology Department of The Municipal Hospital Filantropia, Craiova, between October 2016 and May 2020. The ultrasound evaluation in the second trimester was performed during the second trimester morphology scan, or after this, but up to 24 weeks of pregnancy.

RESULTS: The study showed only in the case of early preeclampsia (PE) a statistical significance for mean PI-UtA percentiles in the second trimester. In the other studied categories of pregnancy outcome, even we did not have a statistical significance, we found a specificity of 75% and positive predictive value of 88.89% in late PE. The presence of notch in the second trimester was statistically significant (p value <0.05) in the case of premature birth (PB) and early PE. A positive predictive value of 77.50% we found only in case of late PE.

CONCLUSIONS: Our results show that routine Doppler screening of the uterine arteries during the second trimester did not make an accurate prediction of fetal growth restriction, preeclampsia or preterm birth. However, we believe that the present study results prove that this screening may select a population with increased risk of adverse outcome, which would give them the opportunity to benefit from an early intervention.

Copyright © 2014, Medical University Publishing House Craiova.

Keywords: Doppler; Pregnancy; high risk

Conflict of interest statement

None to declare.

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