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Das Adhikari U, Eng G, Farcasanu M, et al. Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival. Clin Infect Dis. 2021;doi: 10.1093/cid/ciab623.
Das Adhikari, U., Eng, G., Farcasanu, M., Avena, L. E., Choudhary, M. C., Triant, V. A., Flagg, M., Schiff, A. E., Gomez, I., Froehle, L. M., Diefenbach, T. J., Ronsard, L., Lingwood, D., Lee, G. C., Rabi, S. A., Erstad, D., Velmahos, G., Li, J. Z., Hodin, R., Stone, J. R., Honko, A. N., Griffiths, A., Yilmaz, O., & Kwon, D. S. (2021). Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, . https://doi.org/10.1093/cid/ciab623
Das Adhikari, Upasana, et al. "Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America vol. (2021). doi: https://doi.org/10.1093/cid/ciab623
Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz O, Kwon DS. Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival. Clin Infect Dis. 2021 Jul 10; doi: 10.1093/cid/ciab623. Epub 2021 Jul 10. PMID: 34245255; PMCID: PMC8406863.
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Clin Infect Dis. 2021 Jul 10; doi: 10.1093/cid/ciab623. Epub 2021 Jul 10.

Fecal SARS-CoV-2 RNA is associated with decreased COVID-19 survival.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Upasana Das Adhikari, George Eng, Mara Farcasanu, Laura E Avena, Manish C Choudhary, Virginia A Triant, Meaghan Flagg, Abigail E Schiff, Isabella Gomez, Leah M Froehle, Thomas J Diefenbach, Larance Ronsard, Daniel Lingwood, Grace C Lee, Seyed Alireza Rabi, Derek Erstad, George Velmahos, Jonathan Z Li, Richard Hodin, James R Stone, Anna N Honko, Anthony Griffiths, Omer Yilmaz, Douglas S Kwon

Affiliations

  1. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139 USA.
  2. Harvard Medical School, Boston, MA 02114 USA.
  3. Department of Pathology, Massachusetts General Hospital, Boston, MA 02114 USA.
  4. Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.
  5. Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, MA 02118 United States.
  6. Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA 02115 USA.
  7. Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114 USA.
  8. Division of Surgery, Massachusetts General Hospital, Boston, MA 02114 USA.

PMID: 34245255 PMCID: PMC8406863 DOI: 10.1093/cid/ciab623

Abstract

The clinical significance of SARS CoV-2 RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal (GI) tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased COVID-19 survival. Measurement of SARS-CoV-2 RNA in stool may have utility for clinical risk assessment.

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: [email protected].

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